SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 6 ASP A  99
LEU A 118
VAL A 119
ILE A 117
 None
 1.03A 1s9qA-1qv9A:
0.0		 1s9qA-1qv9A:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 11 LEU A 148
LEU A 144
PRO A  75
ASN A  74
LEU A  23
 None
 1.34A 2ft9A-1qv9A:
undetectable		 2ft9A-1qv9A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 6 ASP A  25
ARG A  30
ASP A 269
ASP A 162
 None
 1.06A 2j2pE-1qv9A:
undetectable
2j2pF-1qv9A:
undetectable		 2j2pE-1qv9A:
20.92
2j2pF-1qv9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A  83
GLY A  39
CYH A  11
LYS A  10
 None
 1.30A 2yldA-1qv9A:
undetectable		 2yldA-1qv9A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A  83
GLY A  39
CYH A  11
LYS A  10
 None
 0.99A 2ylgA-1qv9A:
undetectable		 2ylgA-1qv9A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 8 PHE A   8
PHE A 161
PHE A  67
ALA A  94
 None
 0.90A 3t3sF-1qv9A:
undetectable		 3t3sF-1qv9A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A  83
GLY A  39
CYH A  11
LYS A  10
 None
 1.31A 3zwiA-1qv9A:
undetectable		 3zwiA-1qv9A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 8 MET A 200
GLU A 193
GLU A 192
ARG A 155
 None
 1.16A 4mj8B-1qv9A:
1.6
4mj8C-1qv9A:
0.6		 4mj8B-1qv9A:
22.26
4mj8C-1qv9A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 12 GLY A  72
GLY A  12
MET A  44
ILE A  96
LEU A 118
 None
 1.12A 4mwzA-1qv9A:
undetectable		 4mwzA-1qv9A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		3 / 3 ASP A 122
VAL A 147
LEU A 207
 None
 0.56A 5e5jB-1qv9A:
undetectable		 5e5jB-1qv9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A  83
GLY A  39
CYH A  11
LYS A  10
 None
 1.03A 5jliA-1qv9A:
undetectable		 5jliA-1qv9A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A  83
GLY A  39
CYH A  11
LYS A  10
 None
 1.09A 5jt4A-1qv9A:
undetectable		 5jt4A-1qv9A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 11 ILE A   9
ILE A  68
VAL A  38
ILE A  59
ALA A  60
 None
 1.11A 5lg3A-1qv9A:
3.5		 5lg3A-1qv9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 12 ILE A   9
ILE A  68
VAL A  38
ILE A  59
ALA A  60
 None
 1.05A 5lg3E-1qv9A:
3.5		 5lg3E-1qv9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 10 PRO A  80
ILE A  96
PRO A  75
SER A  17
GLY A  98
 None
 1.28A 5weoA-1qv9A:
2.0
5weoD-1qv9A:
2.2		 5weoA-1qv9A:
14.39
5weoD-1qv9A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_B_CYZB1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 9 PRO A  80
ILE A  96
PRO A  75
SER A  17
GLY A  98
 None
 1.27A 5weoB-1qv9A:
2.4
5weoC-1qv9A:
4.5		 5weoB-1qv9A:
14.39
5weoC-1qv9A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_D_CYZD1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 9 ILE A  96
PRO A  75
SER A  17
GLY A  98
PRO A  80
 None
 1.27A 5weoA-1qv9A:
1.9
5weoD-1qv9A:
2.2		 5weoA-1qv9A:
14.39
5weoD-1qv9A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 5 ALA A 214
SER A 217
GLY A 126
TYR A 140
 None
 1.22A 5yodD-1qv9A:
undetectable		 5yodD-1qv9A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZGB_B_PQNB844_1
(PSAB)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 9 ILE A   7
MET A 109
ALA A  83
LEU A  87
ALA A  88
 None
 1.21A 5zgbB-1qv9A:
2.9		 5zgbB-1qv9A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZGH_B_PQNB843_1
(PSAB)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		5 / 9 ILE A   7
MET A 109
ALA A  83
LEU A  87
ALA A  88
 None
 1.16A 5zghB-1qv9A:
2.4		 5zghB-1qv9A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 4 ALA A 203
ALA A 206
ALA A 248
ALA A 251
 None
 0.82A 6gtqA-1qv9A:
0.0
6gtqB-1qv9A:
0.0		 6gtqA-1qv9A:
22.07
6gtqB-1qv9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE
(Methanopyrus
kandleri) 		4 / 4 ALA A 248
ALA A 251
ALA A 203
ALA A 206
 None
 0.83A 6gtqA-1qv9A:
0.0
6gtqB-1qv9A:
0.0		 6gtqA-1qv9A:
22.07
6gtqB-1qv9A:
22.07