SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 199
THR A  14
ILE A 221
ILE A 167
ALA A  79
 None
 1.01A 3vw1D-1qvaA:
undetectable		 3vw1D-1qvaA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 138
GLU A 134
GLY A 135
 None
 0.61A 3w9tA-1qvaA:
undetectable		 3w9tA-1qvaA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 5 CYH A 123
LEU A  93
LEU A 189
LEU A  95
 None
 1.13A 4n09D-1qvaA:
4.0		 4n09D-1qvaA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 147
PRO A 146
ALA A  96
 None
 0.49A 4qn9B-1qvaA:
0.8		 4qn9B-1qvaA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 9 PRO A  54
TYR A  16
ILE A 221
VAL A  19
ILE A  47
 None
 1.28A 5mzrD-1qvaA:
undetectable		 5mzrD-1qvaA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 8 GLN A  48
ILE A  12
THR A  14
TYR A  16
 None
 1.07A 6cduG-1qvaA:
undetectable
6cduH-1qvaA:
undetectable		 6cduG-1qvaA:
19.76
6cduH-1qvaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1qva INITIATION FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  77
GLN A  48
GLU A  43
VAL A  36
 None
 0.98A 6j20A-1qvaA:
undetectable		 6j20A-1qvaA:
20.55