SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1qvp DIPHTHERIA TOXIN
REPRESSOR
(Corynebacterium
diphtheriae) 		5 / 12 VAL A 166
THR A 220
ILE A 187
VAL A 193
ILE A 195
 None
 1.20A 4eb6B-1qvpA:
undetectable
4eb6C-1qvpA:
undetectable		 4eb6B-1qvpA:
11.94
4eb6C-1qvpA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1qvp DIPHTHERIA TOXIN
REPRESSOR
(Corynebacterium
diphtheriae) 		3 / 3 GLU A 212
HIS A 201
ASP A 177
 None
 0.81A 5c0oG-1qvpA:
undetectable		 5c0oG-1qvpA:
20.60