SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 PHE A 593
ALA A 605
LEU A 608
VAL A 703
 None
 0.84A 1hk2A-1qvrA:
undetectable		 1hk2A-1qvrA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 ALA A 305
LEU A 302
PHE A 324
LEU A 320
ILE A 314
 None
 1.15A 1rb2B-1qvrA:
undetectable		 1rb2B-1qvrA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 4 ILE A 715
ASP A 730
LEU A 736
ARG A 755
 None
 1.36A 2a7qA-1qvrA:
1.2		 2a7qA-1qvrA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 6 ARG A 450
GLU A 407
ILE A 403
PRO A 400
 None
 0.83A 2fcnA-1qvrA:
undetectable
2fcnB-1qvrA:
undetectable		 2fcnA-1qvrA:
6.99
2fcnB-1qvrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 VAL A 258
LEU A 186
THR A 161
ASP A 159
 None
 1.05A 2hdnF-1qvrA:
undetectable
2hdnG-1qvrA:
undetectable
2hdnH-1qvrA:
undetectable		 2hdnF-1qvrA:
18.17
2hdnG-1qvrA:
3.91
2hdnH-1qvrA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 VAL A 570
ILE A 705
THR A 707
LEU A 665
LEU A 556
 None
 1.22A 2jn3A-1qvrA:
undetectable		 2jn3A-1qvrA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A  20
LEU A  14
ALA A  13
LEU A 115
LEU A  39
 None
 0.97A 2oaxB-1qvrA:
undetectable		 2oaxB-1qvrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A  20
LEU A  14
ALA A  13
LEU A 115
LEU A  39
 None
 0.96A 2oaxD-1qvrA:
undetectable		 2oaxD-1qvrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A  20
LEU A  14
ALA A  13
LEU A 115
LEU A  39
 None
 0.98A 2oaxE-1qvrA:
undetectable		 2oaxE-1qvrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 5 LEU A 232
VAL A 108
LEU A  38
ARG A  11
 None
 1.11A 2oiqA-1qvrA:
undetectable		 2oiqA-1qvrA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 6 SER A 539
TYR A 371
VAL A 530
ASP A 614
 None
 1.42A 2x45A-1qvrA:
undetectable		 2x45A-1qvrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 SER A 539
TYR A 371
ILE A 536
ASP A 614
 None
 1.21A 2x45B-1qvrA:
undetectable		 2x45B-1qvrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 SER A 539
TYR A 371
ILE A 536
ASP A 614
 None
 1.22A 2x45C-1qvrA:
undetectable		 2x45C-1qvrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 ILE A 266
LEU A 224
ARG A 189
ILE A 183
VAL A 327
 None
 1.11A 2ygnA-1qvrA:
undetectable		 2ygnA-1qvrA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 11 MET A 624
LEU A 680
VAL A 676
ILE A 664
LEU A 652
 PT  A 862 (-2.2A)
None
None
None
None
 1.20A 3fl9C-1qvrA:
undetectable		 3fl9C-1qvrA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 10 MET A 624
LEU A 680
VAL A 676
ILE A 664
LEU A 652
 PT  A 862 (-2.2A)
None
None
None
None
 1.16A 3fl9E-1qvrA:
undetectable		 3fl9E-1qvrA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 9 VAL A 182
PHE A 268
ILE A 303
ALA A 206
VAL A 329
 None
None
None
ANP  A 901 (-3.2A)
None
 1.13A 3me6C-1qvrA:
undetectable		 3me6C-1qvrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 9 VAL A 182
PHE A 268
ILE A 303
ALA A 206
VAL A 329
 None
None
None
ANP  A 901 (-3.2A)
None
 1.03A 3me6D-1qvrA:
1.3		 3me6D-1qvrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 578
LEU A 549
THR A 611
 None
 0.91A 3oxcA-1qvrA:
0.0		 3oxcA-1qvrA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 5 GLN A 142
HIS A 145
ARG A 162
GLU A 166
 None
 1.44A 3r4xA-1qvrA:
undetectable		 3r4xA-1qvrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 ASP A  41
GLN A  16
GLU A 257
ARG A 297
 None
 1.15A 3s3oA-1qvrA:
undetectable		 3s3oA-1qvrA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 LEU A 592
LEU A 706
GLU A 668
ILE A 669
 None
 0.92A 3s56B-1qvrA:
undetectable		 3s56B-1qvrA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 10 ALA A 389
ILE A 529
ILE A 382
ALA A 360
VAL A 521
 None
None
ANP  A 901 (-4.5A)
None
None
 1.02A 3t3cB-1qvrA:
undetectable		 3t3cB-1qvrA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		6 / 12 LEU A 132
GLY A  96
VAL A 106
THR A 110
LEU A 101
GLY A  89
 None
 1.40A 4dc3B-1qvrA:
undetectable		 4dc3B-1qvrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 PHE A 740
PHE A 744
ALA A 672
LEU A 706
 None
 1.01A 4ejgA-1qvrA:
0.0		 4ejgA-1qvrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 6 ARG A 475
GLY A 167
GLU A 478
GLN A 142
 None
 1.24A 4g0vB-1qvrA:
2.8		 4g0vB-1qvrA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 10 ARG A 342
ILE A 361
ILE A 526
ALA A 363
VAL A 334
 None
 1.33A 4kq8A-1qvrA:
undetectable		 4kq8A-1qvrA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 LEU A 786
LEU A 808
LEU A 773
ILE A 765
 None
None
None
ANP  A 911 (-4.1A)
 1.03A 4okwA-1qvrA:
undetectable		 4okwA-1qvrA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 GLN A 142
HIS A 145
ARG A 162
 None
 1.26A 4qyqA-1qvrA:
undetectable		 4qyqA-1qvrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_D_3CJD607_1
(LACTOPEROXIDASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 4 GLN A 142
HIS A 145
ARG A 162
GLU A 166
 None
 1.49A 4qyqD-1qvrA:
0.0		 4qyqD-1qvrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 GLU A 257
TYR A 150
GLU A 154
ARG A  48
 None
 1.40A 4r87J-1qvrA:
0.2
4r87L-1qvrA:
0.0		 4r87J-1qvrA:
12.43
4r87L-1qvrA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 8 GLY A  96
GLU A 100
GLU A 117
ALA A 118
 None
 0.84A 4rjdA-1qvrA:
0.0
4rjdB-1qvrA:
0.0		 4rjdA-1qvrA:
5.41
4rjdB-1qvrA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 THR A 119
ALA A 116
LEU A 128
LEU A 125
PRO A  57
 None
 1.24A 4xi3D-1qvrA:
undetectable		 4xi3D-1qvrA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 139
ASP A 109
TYR A 150
 None
 0.88A 4yo9B-1qvrA:
undetectable		 4yo9B-1qvrA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 5 GLY A 226
GLY A 223
GLU A 222
 None
 0.42A 4z2eA-1qvrA:
undetectable
4z2eD-1qvrA:
undetectable		 4z2eA-1qvrA:
21.21
4z2eD-1qvrA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 ASN A 193
LEU A 224
PHE A 268
 None
 0.77A 5dsgA-1qvrA:
undetectable		 5dsgA-1qvrA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 11 ALA A  90
ALA A 114
LEU A 111
LEU A  14
VAL A 106
 None
 1.26A 5eb5A-1qvrA:
undetectable		 5eb5A-1qvrA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_D_3CJD609_1
(LACTOPEROXIDASE)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 4 GLN A 142
HIS A 145
ARG A 162
GLU A 166
 None
 1.49A 5hpwD-1qvrA:
0.0		 5hpwD-1qvrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 LEU A 302
THR A 306
THR A 307
LEU A 291
 None
 0.82A 5jq7B-1qvrA:
0.0		 5jq7B-1qvrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 ALA A 605
LEU A 608
ALA A 609
PHE A 613
THR A 615
 None
 1.05A 5k9dA-1qvrA:
1.2		 5k9dA-1qvrA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 11 ILE A 704
GLU A 668
ASP A 667
ILE A 669
ALA A 672
 None
 1.12A 5lg3A-1qvrA:
2.8		 5lg3A-1qvrA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 ILE A 704
GLU A 668
ASP A 667
ILE A 669
ALA A 672
 None
 1.06A 5lg3E-1qvrA:
2.7		 5lg3E-1qvrA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 160
VAL A 258
LEU A 211
PRO A 194
ILE A 303
 None
 1.36A 5uahC-1qvrA:
0.0		 5uahC-1qvrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 8 ARG A 621
LYS A 606
ALA A 605
GLY A 600
 None
None
None
ANP  A 911 (-2.9A)
 0.97A 5v0vA-1qvrA:
2.0		 5v0vA-1qvrA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 6 ILE A 751
ILE A 683
LEU A 680
PHE A 744
 None
 0.96A 5vkqB-1qvrA:
5.8
5vkqC-1qvrA:
5.8		 5vkqB-1qvrA:
19.75
5vkqC-1qvrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 6 ILE A 751
ILE A 683
LEU A 680
PHE A 744
 None
 0.96A 5vkqC-1qvrA:
5.8
5vkqD-1qvrA:
5.8		 5vkqC-1qvrA:
19.75
5vkqD-1qvrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 344
GLY A 203
THR A 205
VAL A 208
PHE A 268
 ANP  A 901 (-4.6A)
ANP  A 901 (-3.0A)
ANP  A 901 (-3.2A)
None
None
 1.15A 5x6yA-1qvrA:
2.8		 5x6yA-1qvrA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		4 / 7 VAL A 208
VAL A 327
PRO A 194
GLY A 304
 None
 0.93A 5x80C-1qvrA:
undetectable
5x80D-1qvrA:
undetectable		 5x80C-1qvrA:
12.12
5x80D-1qvrA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 578
PHE A 613
ARG A 370
 None
 1.26A 5y9yA-1qvrA:
0.0		 5y9yA-1qvrA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1qvr CLPB PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 342
LYS A 345
ARG A 518
 None
 1.21A 6c06D-1qvrA:
6.1		 6c06D-1qvrA:
undetectable