SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1qw2 CONSERVED
HYPOTHETICAL PROTEIN
TA1206
(Thermoplasma
acidophilum) 		3 / 3 GLY A  69
ASP A  70
SER A  93
 None
 0.52A 2qhfA-1qw2A:
undetectable		 2qhfA-1qw2A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1qw2 CONSERVED
HYPOTHETICAL PROTEIN
TA1206
(Thermoplasma
acidophilum) 		4 / 7 GLN A  94
LEU A  60
VAL A  89
LEU A 114
 None
 0.91A 3g8iA-1qw2A:
undetectable		 3g8iA-1qw2A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 1qw2 CONSERVED
HYPOTHETICAL PROTEIN
TA1206
(Thermoplasma
acidophilum) 		5 / 12 GLY A  29
TYR A  33
ILE A  26
LEU A  81
ASP A  82
 None
 0.86A 3gwvA-1qw2A:
undetectable		 3gwvA-1qw2A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qw2 CONSERVED
HYPOTHETICAL PROTEIN
TA1206
(Thermoplasma
acidophilum) 		3 / 3 GLY A  58
PRO A  44
LEU A  46
 None
 0.58A 3hcpB-1qw2A:
undetectable		 3hcpB-1qw2A:
12.50