SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 100
SER A 102
TYR A 139
LEU A 137
 None
 1.21A 1xz1A-1qwiA:
undetectable		 1xz1A-1qwiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 100
SER A 102
TYR A 139
LEU A 137
 None
 1.21A 1xz3A-1qwiA:
undetectable		 1xz3A-1qwiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		4 / 7 THR A  80
ILE A  78
PHE A 114
ILE A 118
 None
 0.87A 2y7wC-1qwiA:
undetectable		 2y7wC-1qwiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		3 / 3 TYR A 139
ASP A 110
ASP A 115
 None
 0.66A 3r24A-1qwiA:
undetectable		 3r24A-1qwiA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		5 / 8 ALA A  82
ILE A  98
LEU A 100
ALA A  55
ALA A  58
 None
 1.38A 3r9tA-1qwiA:
undetectable		 3r9tA-1qwiA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		5 / 8 LEU A  29
GLY A  27
VAL A  28
LEU A  51
GLY A   7
 None
 1.27A 4zauA-1qwiA:
undetectable		 4zauA-1qwiA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1qwi OSMOTICALLY
INDUCIBLE PROTEIN
(Escherichia
coli) 		4 / 8 THR A  24
GLN A   8
THR A  21
LYS A  19
 None
 1.13A 6c06C-1qwiA:
undetectable		 6c06C-1qwiA:
undetectable