SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1WRL_C_TFPC208_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1qx2	VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL (Bos taurus)	4 / 5	PHE A 13 PHE A 66 MET A 70 SER A 74	None	1.23A	1wrlC-1qx2A: 8.2	1wrlC-1qx2A: 38.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3P_A_ACTA1223_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15)	1qx2	VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL (Bos taurus)	4 / 5	ASP A 47 THR A 45 LEU A 46 LYS A 25	None	1.50A	4a3pA-1qx2A: undetectable	4a3pA-1qx2A: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA506_0 (RNA POLYMERASE 3D-POL)	1qx2	VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL (Bos taurus)	3 / 3	VAL A 61 GLY A 59 LYS A 25	None	0.76A	4k50A-1qx2A: undetectable	4k50A-1qx2A: 11.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RJD_A_TFPA203_1 (CALMODULIN)	1qx2	VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL (Bos taurus)	4 / 8	PHE A 13 ILE A 23 VAL A 61 MET A 69	None	0.54A	4rjdA-1qx2A: 7.7	4rjdA-1qx2A: 45.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_C_TFPC208_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1qx2","VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL","Bos taurus",4,"PHE A  13;PHE A  66;MET A  70;SER A  74","None","1.23A","1wrlC-1qx2A:8.2","1wrlC-1qx2A:38.20"],["4A3P_A_ACTA1223_0","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15","1qx2","VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL","Bos taurus",4,"ASP A  47;THR A  45;LEU A  46;LYS A  25","None","1.50A","4a3pA-1qx2A:undetectable","4a3pA-1qx2A:16.11"],["4K50_A_ACTA506_0","RNA POLYMERASE 3D-POL","1qx2","VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL","Bos taurus",3,"VAL A  61;GLY A  59;LYS A  25","None","0.76A","4k50A-1qx2A:undetectable","4k50A-1qx2A:11.76"],["4RJD_A_TFPA203_1","CALMODULIN","1qx2","VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN, INTESTINAL","Bos taurus",4,"PHE A  13;ILE A  23;VAL A  61;MET A  69","None","0.54A","4rjdA-1qx2A:7.7","4rjdA-1qx2A:45.21"]]