SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qx6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		5 / 10 VAL A 235
VAL A 237
SER A 171
PHE A 195
ASN A 124
 None
 1.50A 4ldoA-1qx6A:
undetectable		 4ldoA-1qx6A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		4 / 8 PHE A 195
THR A 199
VAL A 237
PHE A 170
 None
 0.93A 4ltwA-1qx6A:
undetectable		 4ltwA-1qx6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		4 / 7 ARG A 233
PHE A 114
ARG A 115
ASP A 113
 E64  A 245 (-2.3A)
E64  A 245 (-3.8A)
None
None
 1.49A 5a06A-1qx6A:
undetectable		 5a06A-1qx6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		4 / 7 ARG A 233
PHE A 114
ARG A 115
ASP A 113
 E64  A 245 (-2.3A)
E64  A 245 (-3.8A)
None
None
 1.48A 5a06C-1qx6A:
undetectable		 5a06C-1qx6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		4 / 7 ARG A 233
PHE A 114
ARG A 115
ASP A 113
 E64  A 245 (-2.3A)
E64  A 245 (-3.8A)
None
None
 1.47A 5a06F-1qx6A:
undetectable		 5a06F-1qx6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		4 / 6 MET A  50
TYR A 165
GLU A 157
GLY A 163
 None
 0.86A 5x7pB-1qx6A:
undetectable		 5x7pB-1qx6A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1qx6 NPQTN SPECIFIC
SORTASE B
(Staphylococcus
aureus) 		5 / 12 VAL A 235
VAL A 237
PHE A 195
ASN A 180
ASN A 124
 None
 1.43A 6h7mB-1qx6A:
undetectable		 6h7mB-1qx6A:
15.62