SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 4 ASP A 209
HIS A 254
ARG A 202
GLU A 207
 None
 0.97A 1lquA-1qy9A:
undetectable		 1lquA-1qy9A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 ALA A  48
ILE A  60
VAL A  82
LEU A  87
ILE A 107
 None
 1.14A 1xozA-1qy9A:
undetectable		 1xozA-1qy9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 7 ALA A  75
THR A  76
ALA A  79
ARG A  83
 None
 0.84A 2ql8A-1qy9A:
undetectable
2ql8B-1qy9A:
undetectable		 2ql8A-1qy9A:
18.52
2ql8B-1qy9A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 8 GLY A 160
HIS A 161
ILE A 281
ALA A 100
 None
GOL  A1000 (-3.9A)
None
None
 0.81A 2x0pA-1qy9A:
0.0		 2x0pA-1qy9A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		3 / 3 ASN A 247
HIS A 244
VAL A 237
 None
 0.83A 3elzB-1qy9A:
undetectable		 3elzB-1qy9A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 7 VAL A 105
LEU A 118
SER A 117
VAL A  77
 None
 0.89A 3hs6B-1qy9A:
undetectable		 3hs6B-1qy9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 10 ILE A 166
ALA A 136
THR A 133
ILE A 191
VAL A 164
 None
 1.10A 3me6A-1qy9A:
0.0		 3me6A-1qy9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 ASP A 113
VAL A  77
ALA A  78
TYR A  81
VAL A  82
 None
 1.10A 4mm4B-1qy9A:
undetectable		 4mm4B-1qy9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 8 ALA A 234
PRO A 276
VAL A 279
ALA A 157
GLY A 124
 None
 1.39A 4zjzB-1qy9A:
undetectable		 4zjzB-1qy9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 6 ARG A 211
GLY A 256
GLU A 221
ARG A 202
 None
 1.09A 5btaA-1qy9A:
0.4
5btaB-1qy9A:
undetectable
5btaC-1qy9A:
undetectable		 5btaA-1qy9A:
21.19
5btaB-1qy9A:
21.05
5btaC-1qy9A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 5 ARG A 211
GLY A 256
GLU A 221
ARG A 202
 None
 1.14A 5cdqA-1qy9A:
undetectable
5cdqB-1qy9A:
undetectable
5cdqC-1qy9A:
undetectable		 5cdqA-1qy9A:
20.00
5cdqB-1qy9A:
22.48
5cdqC-1qy9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 ILE A  60
VAL A  82
GLU A 108
ALA A 285
VAL A   8
 None
 0.92A 5igjA-1qy9A:
0.0		 5igjA-1qy9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 ILE A  60
VAL A  82
GLU A 108
ALA A 285
VAL A   8
 None
 0.93A 5igpA-1qy9A:
undetectable		 5igpA-1qy9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 ILE A  60
VAL A  82
GLU A 108
ALA A 285
VAL A   8
 None
 0.94A 5igtA-1qy9A:
0.5		 5igtA-1qy9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 GLY A  18
ASP A 222
VAL A 224
THR A 225
ALA A 285
 None
None
None
GOL  A1000 (-4.3A)
None
 1.16A 5kpcB-1qy9A:
undetectable		 5kpcB-1qy9A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 10 HIS A   7
ALA A  21
SER A  45
THR A 284
PRO A 223
 None
 1.40A 5mm4B-1qy9A:
undetectable		 5mm4B-1qy9A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		4 / 5 LEU A 149
LEU A 152
MET A 232
GLN A 200
 None
 1.16A 5uc3A-1qy9A:
undetectable		 5uc3A-1qy9A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 1qy9 HYPOTHETICAL PROTEIN
YDDE
(Escherichia
coli) 		5 / 12 GLY A 256
VAL A 220
ILE A 281
GLY A 253
ALA A 228
 None
 1.21A 6c2mB-1qy9A:
undetectable		 6c2mB-1qy9A:
13.59