SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qye'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1qye ENDOPLASMIN
(Canis
lupus) 		4 / 7 LEU A 249
ILE A 247
ASN A 107
PHE A 199
 None
None
CDY  A 338 (-4.1A)
None
 0.95A 2opxA-1qyeA:
undetectable		 2opxA-1qyeA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1qye ENDOPLASMIN
(Canis
lupus) 		4 / 4 LEU A 241
GLY A 242
GLY A 244
THR A 150
 None
 0.89A 3si7A-1qyeA:
undetectable		 3si7A-1qyeA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1qye ENDOPLASMIN
(Canis
lupus) 		4 / 6 ASN A 239
GLY A 238
ASP A 235
ILE A 222
 None
 0.67A 3w9tF-1qyeA:
undetectable		 3w9tF-1qyeA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 1qye ENDOPLASMIN
(Canis
lupus) 		3 / 3 CYH A 138
LYS A 137
HIS A 146
 None
 1.25A 5js5A-1qyeA:
undetectable		 5js5A-1qyeA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1qye ENDOPLASMIN
(Canis
lupus) 		3 / 3 LEU A 159
GLY A 164
PHE A 203
 None
 0.54A 6exiC-1qyeA:
undetectable		 6exiC-1qyeA:
14.55