SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qyi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.81A 1a7yB-1qyiA:
undetectable		 1a7yB-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.77A 1a7yB-1qyiA:
undetectable		 1a7yB-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 ARG A 370
ILE A   4
LEU A 373
ILE A 339
THR A 343
 None
 1.28A 1d1gA-1qyiA:
undetectable		 1d1gA-1qyiA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.82A 1i3wE-1qyiA:
undetectable		 1i3wE-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.80A 1i3wG-1qyiA:
undetectable		 1i3wG-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.85A 1i3wG-1qyiA:
undetectable		 1i3wG-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.83A 1i3wH-1qyiA:
undetectable		 1i3wH-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A 148
LEU A 166
LEU A 151
SER A  86
 None
 1.01A 1i7zA-1qyiA:
undetectable		 1i7zA-1qyiA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 9 THR A 238
GLY A 239
GLY A 322
SER A 324
GLY A  10
 None
 1.28A 1jhoA-1qyiA:
undetectable		 1jhoA-1qyiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 9 THR A 238
GLY A 239
GLY A 322
SER A 324
GLY A  10
 None
 1.30A 1jhrA-1qyiA:
undetectable		 1jhrA-1qyiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 9 THR A 238
GLY A 239
GLY A 322
SER A 324
GLY A  10
 None
 1.30A 1l5lA-1qyiA:
undetectable		 1l5lA-1qyiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.81A 1qfiB-1qyiA:
undetectable		 1qfiB-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.71A 1unjF-1qyiA:
undetectable		 1unjF-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.82A 1unjF-1qyiA:
undetectable		 1unjF-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.78A 1unjL-1qyiA:
undetectable		 1unjL-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.84A 1unjL-1qyiA:
undetectable		 1unjL-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.81A 1unjR-1qyiA:
undetectable		 1unjR-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.82A 1unjR-1qyiA:
undetectable		 1unjR-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.85A 1unjW-1qyiA:
undetectable		 1unjW-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.79A 1unjX-1qyiA:
undetectable		 1unjX-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.83A 1unjX-1qyiA:
undetectable		 1unjX-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.80A 1unmE-1qyiA:
undetectable		 1unmE-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.86A 1unmF-1qyiA:
undetectable		 1unmF-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.84A 1unmF-1qyiA:
undetectable		 1unmF-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 243
THR A 245
PRO A 241
 None
 0.83A 209dC-1qyiA:
undetectable		 209dC-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 PHE A 249
THR A 238
VAL A  11
GLY A  10
 None
 0.92A 2a1mA-1qyiA:
undetectable		 2a1mA-1qyiA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A 249
THR A 238
VAL A  11
GLY A  10
 None
 0.92A 2a1oA-1qyiA:
0.0		 2a1oA-1qyiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A 134
PRO A 133
LEU A 137
 None
 0.60A 2po5B-1qyiA:
2.2		 2po5B-1qyiA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 TYR A 148
SER A  22
THR A  25
ALA A 177
ILE A  83
 None
 1.48A 2qm9B-1qyiA:
undetectable		 2qm9B-1qyiA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.83A 316dC-1qyiA:
undetectable		 316dC-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 5 ILE A 334
SER A 330
PRO A 287
PRO A 285
 None
 1.39A 3bjwC-1qyiA:
undetectable		 3bjwC-1qyiA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 ASP A  51
ASP A  54
ASP A  43
ASP A  32
 None
 1.20A 3havA-1qyiA:
undetectable		 3havA-1qyiA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 SER A 330
ILE A 320
TYR A 290
ASP A   9
 None
 1.09A 3q70A-1qyiA:
undetectable		 3q70A-1qyiA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 122
PHE A 104
LEU A  93
GLY A  37
PHE A  85
 None
 1.26A 3tbgC-1qyiA:
0.0		 3tbgC-1qyiA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 PHE A 167
LEU A  30
ILE A  92
GLN A 116
MET A 105
 None
 1.44A 4a83A-1qyiA:
undetectable		 4a83A-1qyiA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 PHE A 167
LEU A  38
ILE A  92
GLN A 116
MET A 105
 None
 1.31A 4a83A-1qyiA:
undetectable		 4a83A-1qyiA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 TRP A  78
TRP A 174
THR A 175
 None
 1.36A 4bboB-1qyiA:
undetectable		 4bboB-1qyiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 5 VAL A 111
ILE A  87
TYR A  35
ILE A  83
 None
 0.89A 4c8bA-1qyiA:
undetectable		 4c8bA-1qyiA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 LEU A 176
LEU A  29
GLU A  28
TYR A  35
 None
 1.19A 4f3tA-1qyiA:
2.3		 4f3tA-1qyiA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		3 / 3 THR A 245
PRO A 241
THR A 243
 None
 0.81A 4hivD-1qyiA:
undetectable		 4hivD-1qyiA:
2.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 ILE A 101
PHE A 167
LEU A 159
LEU A  89
 None
 0.88A 4qopC-1qyiA:
undetectable		 4qopC-1qyiA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 8 ILE A  83
LEU A 128
LEU A  89
ILE A  92
PHE A  82
 None
 1.44A 4r38D-1qyiA:
undetectable		 4r38D-1qyiA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 ALA A 150
ILE A  83
LEU A 137
PHE A 136
 None
 1.11A 4uymB-1qyiA:
undetectable		 4uymB-1qyiA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qyi HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 GLN A  61
PHE A  60
LEU A 137
PHE A 136
 None
 1.05A 5b1bC-1qyiA:
undetectable
5b1bJ-1qyiA:
undetectable		 5b1bC-1qyiA:
21.23
5b1bJ-1qyiA:
8.71