SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 8 LEU A  20
PHE A 181
VAL A 191
LEU A 174
None
0.95A 1fiqC-1qyrA:
undetectable
1fiqC-1qyrA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
GLU A  66
LEU A  71
ASP A  91
None
0.60A 1jg2A-1qyrA:
9.3
1jg2A-1qyrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 11 GLY A  45
GLY A  47
GLU A  66
LEU A  71
ASP A  91
None
0.65A 1jg3A-1qyrA:
9.2
1jg3A-1qyrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 11 GLY A  45
GLY A  47
GLU A  66
LEU A  71
ASP A  91
None
0.64A 1jg3B-1qyrA:
9.3
1jg3B-1qyrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 8 GLU A  43
GLY A  45
GLU A  66
LEU A  71
ASP A  91
None
0.62A 1jg4A-1qyrA:
9.4
1jg4A-1qyrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 ILE A  44
GLY A  45
GLY A  47
ASN A 113
PRO A 115
None
0.72A 1nv8A-1qyrA:
11.5
1nv8A-1qyrA:
22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 12 PHE A  19
GLU A  43
GLY A  45
GLY A  47
ASP A  68
ASP A  91
ASN A 113
PRO A 115
ILE A 118
None
0.74A 1qaoA-1qyrA:
23.7
1qaoA-1qyrA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 12 PHE A  19
GLU A  43
GLY A  45
GLY A  47
ASP A  68
LEU A  71
ASN A 113
PRO A 115
ILE A 118
None
0.72A 1qaoA-1qyrA:
23.7
1qaoA-1qyrA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
8 / 12 PHE A  19
GLU A  43
GLY A  45
GLY A  47
ASP A  68
LEU A  71
ILE A  65
ASN A 113
None
0.99A 1qaoA-1qyrA:
23.7
1qaoA-1qyrA:
30.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 ILE A  44
GLY A  47
ALA A  50
ASN A 113
PRO A 115
None
0.76A 1sg9C-1qyrA:
11.7
1sg9C-1qyrA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 11 LEU A 148
ILE A 133
LEU A 126
PHE A 138
HIS A 137
None
1.15A 1tw4A-1qyrA:
0.0
1tw4A-1qyrA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
8 / 12 GLY A  47
LEU A  67
LEU A  71
ASP A  91
PRO A 115
ILE A 118
MET A 139
SER A 189
None
0.73A 1zq9A-1qyrA:
27.0
1zq9A-1qyrA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
3 / 3 GLY A  45
GLU A  66
ASN A 113
None
0.52A 1zq9A-1qyrA:
27.0
1zq9A-1qyrA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
7 / 12 GLY A  45
GLY A  47
ASN A 113
LEU A 114
PRO A 115
ILE A 118
PHE A 181
None
1.16A 1zq9B-1qyrA:
26.6
1zq9B-1qyrA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 12 GLY A  45
GLY A  47
LEU A  67
LEU A  71
ASP A  91
ASN A 113
PRO A 115
ILE A 118
PHE A 181
None
0.80A 1zq9B-1qyrA:
26.6
1zq9B-1qyrA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 GLY A 112
ASN A 113
LEU A 114
PRO A 115
ILE A 118
PHE A 181
None
1.21A 1zq9B-1qyrA:
26.6
1zq9B-1qyrA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 11 GLU A  43
GLU A  66
ASP A  68
ASP A  91
PRO A 115
None
0.74A 2admA-1qyrA:
11.8
2admA-1qyrA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
LEU A  51
ASP A  68
ASN A 113
None
0.60A 2nxeA-1qyrA:
12.8
2nxeA-1qyrA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
LEU A  51
ASP A  68
ASN A 113
None
0.60A 2nxeB-1qyrA:
12.8
2nxeB-1qyrA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
LEU A  51
ASP A  68
ASN A 113
None
0.56A 2zbpA-1qyrA:
12.6
2zbpA-1qyrA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 GLY A  45
GLY A  47
ALA A  50
LEU A  51
ASN A 113
PRO A 115
None
0.70A 2zulA-1qyrA:
10.7
2zulA-1qyrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
LEU A  51
ASP A  68
ASN A 113
None
0.63A 3cjtO-1qyrA:
12.7
3cjtO-1qyrA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 8 LEU A 232
ALA A 265
TYR A 257
ILE A 225
None
0.92A 3cldB-1qyrA:
0.0
3cldB-1qyrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 GLY A  45
GLY A  47
ALA A  50
ASP A  91
ASN A 113
PRO A 115
None
0.94A 3dmfA-1qyrA:
10.7
3dmfA-1qyrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 GLY A  45
GLY A  47
ALA A  50
LEU A  51
ASN A 113
PRO A 115
None
0.68A 3dmhA-1qyrA:
10.8
3dmhA-1qyrA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
7 / 11 GLU A  43
GLY A  45
GLY A  47
ILE A  65
GLU A  66
ASP A  91
ALA A  92
None
0.61A 3dxyA-1qyrA:
9.4
3dxyA-1qyrA:
24.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
7 / 12 GLY A  45
GLY A  47
GLU A  66
ASP A  68
ALA A  92
PRO A 115
ILE A 118
None
0.83A 3fuuA-1qyrA:
26.8
3fuuA-1qyrA:
36.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
7 / 12 GLY A  45
GLY A  47
GLU A  66
ASP A  91
ALA A  92
PRO A 115
ILE A 118
None
0.80A 3fuuA-1qyrA:
26.8
3fuuA-1qyrA:
36.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLU A  43
GLY A  47
LEU A  51
LEU A  67
ASP A  91
None
0.76A 3g2oB-1qyrA:
11.5
3g2oB-1qyrA:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 11 GLY A  45
GLY A  47
GLU A  66
ASP A  68
ASP A  91
ALA A  92
ASN A 113
PRO A 115
ILE A 118
None
0.81A 3grvA-1qyrA:
27.7
3grvA-1qyrA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 11 GLY A  45
GLY A  47
GLU A  66
ASP A  68
LEU A  71
ALA A  92
ASN A 113
PRO A 115
ILE A 118
None
0.77A 3grvA-1qyrA:
27.7
3grvA-1qyrA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
10 / 12 LEU A  20
GLU A  43
GLY A  45
GLY A  47
GLU A  66
ASP A  68
ASP A  91
ALA A  92
ASN A 113
PRO A 115
None
0.83A 3gryA-1qyrA:
27.7
3gryA-1qyrA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
10 / 12 LEU A  20
GLU A  43
GLY A  45
GLY A  47
GLU A  66
ASP A  68
LEU A  71
ALA A  92
ASN A 113
PRO A 115
None
0.82A 3gryA-1qyrA:
27.7
3gryA-1qyrA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 LEU A  51
GLY A  47
GLU A  66
ASP A  68
ASP A  91
ALA A  92
None
1.35A 3gryA-1qyrA:
27.7
3gryA-1qyrA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 LEU A  51
GLY A  47
GLU A  66
ASP A  68
LEU A  71
ALA A  92
None
1.35A 3gryA-1qyrA:
27.7
3gryA-1qyrA:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 7 MET A 123
LEU A 114
LEU A 148
PHE A 124
None
1.27A 3nk2X-1qyrA:
undetectable
3nk2X-1qyrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
LEU A  67
ASP A  91
ASN A 113
PRO A 115
None
0.72A 3q87B-1qyrA:
13.2
3q87B-1qyrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 LEU A  20
GLY A  47
ALA A  92
ASN A 113
PRO A 115
None
0.88A 3tm4A-1qyrA:
14.1
3tm4A-1qyrA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 LEU A  20
GLY A  47
ALA A  92
ASN A 113
PRO A 115
None
0.90A 3tm4B-1qyrA:
14.2
3tm4B-1qyrA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 8 LEU A  20
PHE A 181
VAL A 191
LEU A 174
None
0.89A 3uniB-1qyrA:
undetectable
3uniB-1qyrA:
11.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 LEU A  20
GLY A  45
GLY A  47
ASN A 113
PRO A 115
None
0.69A 4gc9A-1qyrA:
27.1
4gc9A-1qyrA:
30.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
6 / 12 GLY A  45
GLY A  47
LEU A  67
ASP A  91
ALA A  92
ILE A 118
None
0.70A 4krhA-1qyrA:
7.4
4krhA-1qyrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 GLY A  45
GLY A  47
LEU A  67
ALA A  92
ILE A 118
None
0.62A 4krhB-1qyrA:
7.4
4krhB-1qyrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 6 LEU A  20
ASN A 113
LEU A 174
VAL A 145
None
1.17A 4okbA-1qyrA:
undetectable
4okbA-1qyrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 7 GLY A  45
GLY A  47
GLU A  66
ASP A  91
None
0.70A 5ergB-1qyrA:
12.2
5ergB-1qyrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 ASP A  91
ALA A  92
PRO A 115
GLY A  47
GLU A  66
None
0.88A 5hfjA-1qyrA:
3.3
5hfjA-1qyrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 ASP A  91
ALA A  92
PRO A 115
GLY A  47
GLU A  66
None
0.83A 5hfjD-1qyrA:
3.1
5hfjD-1qyrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 12 ASP A  91
ALA A  92
PRO A 115
GLY A  47
GLU A  66
None
0.92A 5hfjF-1qyrA:
3.3
5hfjF-1qyrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 10 ALA A  92
ILE A  65
TYR A  88
PHE A  97
VAL A 110
None
1.14A 5i6xA-1qyrA:
undetectable
5i6xA-1qyrA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
5 / 9 ILE A  87
LEU A  85
GLU A  43
THR A  52
GLY A  47
None
1.18A 5ifuB-1qyrA:
undetectable
5ifuB-1qyrA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 7 GLY A  45
GLU A  66
ASP A  91
ASN A 113
None
0.80A 5mvsA-1qyrA:
2.9
5mvsA-1qyrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
4 / 8 GLY A  45
GLU A  66
ASP A  91
ASN A 113
None
0.79A 5mvsB-1qyrA:
9.3
5mvsB-1qyrA:
20.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
8 / 12 PHE A  19
LEU A  20
GLU A  43
GLY A  45
GLY A  47
ALA A  50
ASP A  68
PRO A 115
None
0.77A 6iftA-1qyrA:
28.4
6iftA-1qyrA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli)
9 / 12 PHE A  19
LEU A  20
GLU A  43
ILE A  44
GLY A  45
GLY A  47
ALA A  50
ASP A  68
LEU A  71
None
0.62A 6iftA-1qyrA:
28.4
6iftA-1qyrA:
33.71