SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1qys TOP7
(-) 		5 / 12 ILE A  10
VAL A   6
MET A  37
ILE A  66
VAL A  70
 None
 1.24A 3iw1A-1qysA:
undetectable		 3iw1A-1qysA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1qys TOP7
(-) 		3 / 3 GLU A  59
ASP A  86
ASP A   3
 None
 0.69A 3jb2A-1qysA:
3.8		 3jb2A-1qysA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qys TOP7
(-) 		5 / 12 VAL A   6
ILE A  66
VAL A  70
LEU A  74
LEU A  67
 None
 1.02A 4m11B-1qysA:
undetectable		 4m11B-1qysA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qys TOP7
(-) 		5 / 12 ILE A  79
ALA A  65
ILE A  52
VAL A  90
VAL A  81
 None
 0.85A 4nkxA-1qysA:
undetectable		 4nkxA-1qysA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qys TOP7
(-) 		5 / 12 ILE A  79
ALA A  65
ILE A  52
VAL A  90
VAL A  81
 None
 0.87A 4nkxB-1qysA:
undetectable		 4nkxB-1qysA:
11.85