SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 4 LEU A  83
LEU A 122
SER A 123
LEU A  87
 None
 1.04A 1ya3A-1qzgA:
undetectable		 1ya3A-1qzgA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ALA A 162
PHE A  46
ILE A  22
GLU A 158
 None
 0.74A 2cizA-1qzgA:
undetectable		 2cizA-1qzgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 VAL A  69
ILE A 110
LEU A 107
SER A  33
LEU A 112
 None
 1.09A 4m11C-1qzgA:
0.0		 4m11C-1qzgA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP A  72
GLN A  28
THR A  75
 None
 0.96A 4m2xA-1qzgA:
undetectable		 4m2xA-1qzgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A  45
LEU A  87
THR A 111
ARG A 116
 None
 1.08A 6ew0F-1qzgA:
undetectable		 6ew0F-1qzgA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1qzg PROTECTION OF
TELOMERES PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 LEU A  45
LEU A  87
THR A 111
ARG A 116
 None
 1.08A 6ew0G-1qzgA:
undetectable		 6ew0G-1qzgA:
14.81