SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1qzm ATP-DEPENDENT
PROTEASE LA
(Escherichia
coli) 		4 / 8 GLU A 538
ILE A 570
LEU A 575
VAL A 523
 None
 0.75A 1a29A-1qzmA:
undetectable		 1a29A-1qzmA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 1qzm ATP-DEPENDENT
PROTEASE LA
(Escherichia
coli) 		5 / 12 LEU A 579
GLY A 580
ASP A 562
TYR A 535
ASN A 574
 None
 1.17A 3eeoA-1qzmA:
undetectable		 3eeoA-1qzmA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1qzm ATP-DEPENDENT
PROTEASE LA
(Escherichia
coli) 		5 / 9 ILE A 501
ILE A 532
ILE A 531
TYR A 578
ILE A 529
 None
 1.08A 3zosA-1qzmA:
undetectable		 3zosA-1qzmA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1qzm ATP-DEPENDENT
PROTEASE LA
(Escherichia
coli) 		3 / 3 LEU A 551
LEU A 521
ARG A 504
 None
 0.58A 5hnzB-1qzmA:
undetectable		 5hnzB-1qzmA:
13.59