SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1qzu HYPOTHETICAL PROTEIN
MDS018
(Homo
sapiens) 		5 / 12 VAL A  28
SER A  27
ALA A 101
VAL A  24
LEU A  99
 FMN  A 801 (-4.6A)
FMN  A 801 (-2.7A)
None
None
None
 0.98A 1jg4A-1qzuA:
undetectable		 1jg4A-1qzuA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1qzu HYPOTHETICAL PROTEIN
MDS018
(Homo
sapiens) 		3 / 3 LYS A 131
PRO A 132
LEU A 133
 None
 0.85A 3tpxE-1qzuA:
undetectable		 3tpxE-1qzuA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 1qzu HYPOTHETICAL PROTEIN
MDS018
(Homo
sapiens) 		5 / 12 ILE A  65
PRO A  62
LEU A  33
VAL A  22
THR A 121
 None
 1.06A 4kfjB-1qzuA:
undetectable		 4kfjB-1qzuA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1qzu HYPOTHETICAL PROTEIN
MDS018
(Homo
sapiens) 		3 / 3 ASP A  74
VAL A  51
LEU A  91
 None
 0.62A 5e5jB-1qzuA:
undetectable		 5e5jB-1qzuA:
17.82