SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 1gtnH-1r0lA:
undetectable
1gtnI-1r0lA:
undetectable		 1gtnH-1r0lA:
11.76
1gtnI-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 11 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.09A 1gtnM-1r0lA:
undetectable
1gtnN-1r0lA:
undetectable		 1gtnM-1r0lA:
11.76
1gtnN-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.15A 1gtnU-1r0lA:
undetectable
1gtnV-1r0lA:
undetectable		 1gtnU-1r0lA:
11.76
1gtnV-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 12 ILE A 270
ASP A 265
ILE A  16
ALA A 100
THR A 273
 None
 1.25A 1kijB-1r0lA:
undetectable		 1kijB-1r0lA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 8 MET A 312
ILE A 315
GLU A 313
ILE A 223
MET A 325
 None
 1.36A 1linA-1r0lA:
undetectable		 1linA-1r0lA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		3 / 3 ALA A  35
VAL A   7
TRP A  96
 None
 0.89A 1micA-1r0lA:
undetectable
1micB-1r0lA:
undetectable		 1micA-1r0lA:
3.37
1micB-1r0lA:
3.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 11 ALA A 320
ASP A 372
ALA A 327
ASP A 367
PRO A 359
 None
 1.19A 2admA-1r0lA:
5.2		 2admA-1r0lA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		3 / 3 MET A 325
GLU A 126
ASP A 150
 None
 1.11A 3a25A-1r0lA:
5.0		 3a25A-1r0lA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		4 / 7 GLY A  11
GLY A  14
THR A  20
ALA A 100
 NDP  A 400 (-3.1A)
NDP  A 400 (-3.8A)
None
None
 0.86A 3fpjB-1r0lA:
4.7		 3fpjB-1r0lA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		4 / 6 ILE A 173
GLU A 152
ALA A 175
ASN A 217
 None
 1.07A 3pgyA-1r0lA:
undetectable
3pgyB-1r0lA:
2.1		 3pgyA-1r0lA:
23.06
3pgyB-1r0lA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 ILE A 315
LEU A 228
THR A 273
ILE A 102
ILE A 208
 None
None
None
NDP  A 400 ( 4.9A)
None
 1.22A 3prsA-1r0lA:
undetectable		 3prsA-1r0lA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		3 / 3 ARG A 304
PHE A 305
PRO A 306
 None
 0.78A 3zoaB-1r0lA:
undetectable		 3zoaB-1r0lA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 12 ALA A  54
LEU A  21
SER A  75
GLY A  17
LEU A  10
 None
 1.09A 4dm8B-1r0lA:
undetectable		 4dm8B-1r0lA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		4 / 5 TYR A 302
LEU A 233
GLU A 237
VAL A 168
 None
 1.31A 4nkvA-1r0lA:
undetectable		 4nkvA-1r0lA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eeuF-1r0lA:
undetectable
5eeuG-1r0lA:
undetectable		 5eeuF-1r0lA:
11.76
5eeuG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eeuO-1r0lA:
undetectable
5eeuP-1r0lA:
undetectable		 5eeuO-1r0lA:
11.76
5eeuP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eevF-1r0lA:
undetectable
5eevG-1r0lA:
undetectable		 5eevF-1r0lA:
11.76
5eevG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eevO-1r0lA:
undetectable
5eevP-1r0lA:
undetectable		 5eevO-1r0lA:
11.76
5eevP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eewF-1r0lA:
undetectable
5eewG-1r0lA:
undetectable		 5eewF-1r0lA:
11.76
5eewG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eewO-1r0lA:
undetectable
5eewP-1r0lA:
undetectable		 5eewO-1r0lA:
11.76
5eewP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eexF-1r0lA:
undetectable
5eexG-1r0lA:
undetectable		 5eexF-1r0lA:
11.76
5eexG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eexO-1r0lA:
undetectable
5eexP-1r0lA:
undetectable		 5eexO-1r0lA:
11.76
5eexP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eeyF-1r0lA:
undetectable
5eeyG-1r0lA:
undetectable		 5eeyF-1r0lA:
11.76
5eeyG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eeyO-1r0lA:
undetectable
5eeyP-1r0lA:
undetectable		 5eeyO-1r0lA:
11.76
5eeyP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5eezF-1r0lA:
0.0
5eezG-1r0lA:
undetectable		 5eezF-1r0lA:
11.76
5eezG-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5eezO-1r0lA:
undetectable
5eezP-1r0lA:
undetectable		 5eezO-1r0lA:
11.76
5eezP-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5ef0F-1r0lA:
undetectable
5ef0G-1r0lA:
undetectable		 5ef0F-1r0lA:
11.76
5ef0G-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.10A 5ef0O-1r0lA:
undetectable
5ef0P-1r0lA:
undetectable		 5ef0O-1r0lA:
11.76
5ef0P-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5ef1F-1r0lA:
undetectable
5ef1G-1r0lA:
undetectable		 5ef1F-1r0lA:
11.76
5ef1G-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.11A 5ef1O-1r0lA:
undetectable
5ef1P-1r0lA:
undetectable		 5ef1O-1r0lA:
11.76
5ef1P-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5ef2F-1r0lA:
undetectable
5ef2G-1r0lA:
undetectable		 5ef2F-1r0lA:
11.76
5ef2G-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.11A 5ef2O-1r0lA:
undetectable
5ef2P-1r0lA:
undetectable		 5ef2O-1r0lA:
11.76
5ef2P-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 THR A   8
ALA A  90
GLY A  11
ALA A 109
ILE A 101
 None
None
NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
 1.08A 5ef3F-1r0lA:
undetectable
5ef3G-1r0lA:
undetectable		 5ef3F-1r0lA:
11.76
5ef3G-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 10 GLY A  11
ALA A 109
ILE A 101
THR A   8
ALA A  90
 NDP  A 400 (-3.1A)
None
NDP  A 400 (-3.9A)
None
None
 1.11A 5ef3O-1r0lA:
undetectable
5ef3P-1r0lA:
undetectable		 5ef3O-1r0lA:
11.76
5ef3P-1r0lA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 12 ALA A 123
LEU A 122
ALA A 121
THR A 119
THR A  20
 None
 1.14A 5k9dA-1r0lA:
1.3		 5k9dA-1r0lA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 11 THR A 361
ALA A 320
GLY A 133
GLY A 132
ALA A 131
 None
 0.97A 5lf7Y-1r0lA:
undetectable
5lf7Z-1r0lA:
undetectable		 5lf7Y-1r0lA:
20.82
5lf7Z-1r0lA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		4 / 7 LEU A 292
ILE A 172
THR A 174
MET A 249
 None
 1.00A 5ljcA-1r0lA:
undetectable		 5ljcA-1r0lA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		4 / 8 SER A 314
LEU A 354
ILE A 346
ALA A 347
 None
 0.83A 5te8B-1r0lA:
0.0		 5te8B-1r0lA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W5V_A_ANWA701_0
(SERINE/THREONINE-PRO
TEIN KINASE TBK1)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		5 / 9 LEU A  86
ALA A 109
GLY A  11
THR A  13
THR A  97
 None
None
NDP  A 400 (-3.1A)
NDP  A 400 (-4.1A)
None
 1.23A 5w5vA-1r0lA:
undetectable		 5w5vA-1r0lA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1r0l 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Zymomonas
mobilis) 		3 / 3 TYR A  65
ALA A  71
LEU A  72
 None
 0.57A 6ag0C-1r0lA:
undetectable		 6ag0C-1r0lA:
13.40