SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 8 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.72A 1dz9A-1r0uA:
undetectable		 1dz9A-1r0uA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 8 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.74A 1o76B-1r0uA:
undetectable		 1o76B-1r0uA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 6 LEU A 129
ALA A 117
SER A  99
SER A  82
 None
 0.66A 1tz8C-1r0uA:
undetectable
1tz8D-1r0uA:
undetectable		 1tz8C-1r0uA:
23.53
1tz8D-1r0uA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 6 MET A  89
VAL A 122
LEU A  96
MET A  73
 None
 1.11A 1x8vA-1r0uA:
undetectable		 1x8vA-1r0uA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 8 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.78A 2a1mB-1r0uA:
undetectable		 2a1mB-1r0uA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 7 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.87A 2zaxA-1r0uA:
undetectable		 2zaxA-1r0uA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		5 / 11 ILE A   7
LEU A   9
ILE A 134
VAL A  39
LEU A 107
 None
 1.25A 3a51A-1r0uA:
undetectable		 3a51A-1r0uA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 7 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.85A 3fwgB-1r0uA:
undetectable		 3fwgB-1r0uA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		4 / 7 PHE A  77
TYR A 118
THR A  54
VAL A  56
 None
None
GOL  A 301 ( 4.1A)
None
 0.88A 3fwiA-1r0uA:
undetectable		 3fwiA-1r0uA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 1r0u PROTEIN YWIB
(Bacillus
subtilis) 		3 / 3 TYR A  40
LYS A  38
LYS A  57
 None
 1.05A 5dbyA-1r0uA:
undetectable		 5dbyA-1r0uA:
15.37