SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		7 / 12 GLY A  86
GLY A  88
GLU A 115
LEU A 120
ASP A 147
GLY A 148
ALA A 165
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.2A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.6A)
 0.30A 1jg2A-1r18A:
27.5		 1jg2A-1r18A:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		6 / 11 GLY A  86
GLY A  88
GLU A 115
LEU A 120
ASP A 147
GLY A 148
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.2A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.6A)
 0.21A 1jg3A-1r18A:
27.6		 1jg3A-1r18A:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		6 / 11 GLY A  86
GLY A  88
GLU A 115
LEU A 120
ASP A 147
GLY A 148
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.2A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.7A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.6A)
 0.23A 1jg3B-1r18A:
27.7		 1jg3B-1r18A:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 12 THR A  58
SER A  60
GLY A  88
GLY A 148
ALA A 165
 None
SAH  A 300 ( 4.1A)
SAH  A 300 (-3.2A)
SAH  A 300 (-3.6A)
SAH  A 300 (-3.6A)
 0.47A 1jg4A-1r18A:
28.0		 1jg4A-1r18A:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 8 GLY A  86
SER A  89
GLU A 115
LEU A 120
ASP A 147
 SAH  A 300 (-3.4A)
SAH  A 300 (-2.5A)
SAH  A 300 (-2.9A)
SAH  A 300 (-4.7A)
SAH  A 300 (-3.6A)
 0.23A 1jg4A-1r18A:
28.0		 1jg4A-1r18A:
36.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 11 SER A 124
LEU A 141
SER A  87
ILE A 111
ALA A  31
 None
 1.22A 2zbzA-1r18A:
0.0		 2zbzA-1r18A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 12 GLY A 182
LEU A 184
PRO A 157
ASN A 159
ALA A 160
 None
 0.82A 3av6A-1r18A:
3.1		 3av6A-1r18A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		4 / 5 ILE A  53
SER A  41
PRO A  42
PRO A  45
 None
 1.12A 3bjwC-1r18A:
undetectable		 3bjwC-1r18A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 11 GLY A  86
GLY A  88
ILE A 114
GLU A 115
ASP A 147
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.2A)
None
SAH  A 300 (-2.9A)
SAH  A 300 (-3.6A)
 0.49A 3dxyA-1r18A:
9.2		 3dxyA-1r18A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		5 / 12 VAL A  85
GLY A  86
GLY A  88
GLU A 115
ASP A 147
 None
SAH  A 300 (-3.4A)
SAH  A 300 (-3.2A)
SAH  A 300 (-2.9A)
SAH  A 300 (-3.6A)
 0.46A 3fuuA-1r18A:
8.9		 3fuuA-1r18A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		4 / 4 LEU A 174
ALA A 167
VAL A 188
PRO A 187
 None
 1.02A 3gv1B-1r18A:
undetectable		 3gv1B-1r18A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		4 / 6 GLY A  88
GLU A 115
ASP A 147
ASP A  84
 SAH  A 300 (-3.2A)
SAH  A 300 (-2.9A)
SAH  A 300 (-3.6A)
SAH  A 300 ( 4.9A)
 0.95A 3vywC-1r18A:
8.3		 3vywC-1r18A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		3 / 3 PHE A  96
ILE A  82
ASP A 106
 None
 0.70A 5cswB-1r18A:
undetectable		 5cswB-1r18A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		4 / 5 ARG A  37
HIS A  65
ALA A  61
ASP A  48
 None
SAH  A 300 (-3.9A)
None
None
 1.38A 5mfxA-1r18A:
2.1		 5mfxA-1r18A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 1r18 PROTEIN-L-ISOASPARTA
TE(D-ASPARTATE)-O-ME
THYLTRANSFERASE
(Drosophila
melanogaster) 		4 / 4 GLN A 198
THR A 211
HIS A  75
LEU A  72
 None
 1.43A 6f3nB-1r18A:
5.0		 6f3nB-1r18A:
20.82