SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 5 SER 2 198
GLU 1  38
LEU 1  34
TRP 3 155
 None
 1.42A 1agmA-1r1a2:
undetectable		 1agmA-1r1a2:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 12 THR 3 107
TYR 3 106
ILE 3 102
ILE 3  99
ILE 3 231
 None
 0.94A 1jtxA-1r1a3:
undetectable		 1jtxA-1r1a3:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 12 SER 1 211
THR 2 147
HIS 2 217
TYR 1 194
GLU 2 129
 SUC  1 288 ( 4.5A)
None
None
None
None
 1.20A 1kw0A-1r1a1:
undetectable		 1kw0A-1r1a1:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 11 SER 1 211
THR 2 147
HIS 2 217
TYR 1 194
GLU 2 129
 SUC  1 288 ( 4.5A)
None
None
None
None
 1.23A 1mmtA-1r1a1:
undetectable		 1mmtA-1r1a1:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		3 / 3 ARG 2 165
ASP 1 198
ASN 2 219
 None
 0.94A 1nbhA-1r1a2:
undetectable		 1nbhA-1r1a2:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		3 / 3 ARG 2 165
ASP 1 198
ASN 2 219
 None
 0.94A 1nbhD-1r1a2:
undetectable		 1nbhD-1r1a2:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		3 / 3 ARG 1 223
ARG 1 158
ILE 1 235
 None
 0.62A 1uobA-1r1a1:
undetectable		 1uobA-1r1a1:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 12 ILE 3  44
VAL 3  40
PHE 1 116
LEU 1 115
ILE 2 185
 None
 1.14A 1xozA-1r1a3:
undetectable		 1xozA-1r1a3:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 7 TYR 1 200
THR 2 147
THR 1 265
ASP 1 198
 None
 0.86A 2a1mA-1r1a1:
undetectable		 2a1mA-1r1a1:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		3 / 3 TRP 2 220
THR 1 117
TYR 1 118
 None
 1.21A 2a3aA-1r1a2:
undetectable		 2a3aA-1r1a2:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		3 / 3 TRP 2 220
THR 1 117
TYR 1 118
 None
 1.24A 2a3bA-1r1a2:
undetectable		 2a3bA-1r1a2:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 7 THR 1  42
SER 3 116
ASP 3  50
SER 3 164
VAL 3 166
 None
 1.14A 2hdnE-1r1a1:
undetectable
2hdnF-1r1a1:
undetectable
2hdnH-1r1a1:
undetectable		 2hdnE-1r1a1:
8.64
2hdnF-1r1a1:
21.14
2hdnH-1r1a1:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 7 SER 3 164
VAL 3 166
THR 1  42
SER 3 116
ASP 3  50
 None
 1.16A 2hdnF-1r1a3:
undetectable
2hdnG-1r1a3:
undetectable
2hdnH-1r1a3:
undetectable		 2hdnF-1r1a3:
22.06
2hdnG-1r1a3:
13.33
2hdnH-1r1a3:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 6 THR 1  42
SER 3 116
ASP 3  50
VAL 3 166
 None
 1.21A 2hdnI-1r1a1:
undetectable
2hdnJ-1r1a1:
undetectable
2hdnL-1r1a1:
undetectable		 2hdnI-1r1a1:
8.64
2hdnJ-1r1a1:
21.14
2hdnL-1r1a1:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 6 THR 1  42
SER 3 116
SER 3 164
VAL 3 166
 None
 1.15A 2hdnI-1r1a1:
undetectable
2hdnJ-1r1a1:
undetectable
2hdnL-1r1a1:
undetectable		 2hdnI-1r1a1:
8.64
2hdnJ-1r1a1:
21.14
2hdnL-1r1a1:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 6 SER 3 164
VAL 3 166
THR 1  42
SER 3 116
ASP 3  50
 None
 1.11A 2hdnJ-1r1a3:
undetectable
2hdnK-1r1a3:
undetectable
2hdnL-1r1a3:
undetectable		 2hdnJ-1r1a3:
22.06
2hdnK-1r1a3:
13.33
2hdnL-1r1a3:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 5 ARG 1 181
ASP 3  17
GLU 1 124
LYS 1 242
 None
 1.43A 2xrzA-1r1a1:
undetectable
2xrzB-1r1a1:
undetectable		 2xrzA-1r1a1:
19.10
2xrzB-1r1a1:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		4 / 7 VAL 1 148
ILE 1 154
GLY 1 218
THR 1 219
 None
 0.72A 2xrzB-1r1a1:
undetectable		 2xrzB-1r1a1:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 5 SER 2 195
LEU 2 122
GLY 2 120
GLU 1  38
 None
 0.90A 3aiaA-1r1a2:
undetectable
3aiaB-1r1a2:
undetectable		 3aiaA-1r1a2:
19.63
3aiaB-1r1a2:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 4 VAL 3  49
ARG 1 252
ILE 1  67
THR 3  51
 None
 1.28A 3cl9A-1r1a3:
undetectable		 3cl9A-1r1a3:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 12 GLY 2  77
HIS 2 130
LEU 2 222
VAL 2 110
ILE 2 242
 None
 1.11A 3g9eA-1r1a2:
0.0		 3g9eA-1r1a2:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		4 / 5 PRO 2 226
SER 2  75
LEU 2 180
SER 2 171
 None
 1.41A 3ijxH-1r1a2:
undetectable		 3ijxH-1r1a2:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		4 / 5 PRO 2 226
SER 2  75
LEU 2 180
SER 2 171
 None
 1.46A 3iluH-1r1a2:
undetectable		 3iluH-1r1a2:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A) 		3 / 3 GLU 1  68
ASP 3  18
ASP 1 122
 None
 0.64A 3jb2A-1r1a1:
undetectable		 3jb2A-1r1a1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 8 LEU 3  52
THR 3  51
GLY 3 100
ALA 3  95
ILE 1 278
 None
 1.18A 3jusB-1r1a3:
undetectable		 3jusB-1r1a3:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 9 LEU 3  52
THR 3  51
GLY 3 100
ALA 3  95
ILE 1 278
 None
 1.18A 3jusB-1r1a3:
undetectable		 3jusB-1r1a3:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 11 LEU 3 165
SER 3 116
PHE 3 115
CYH 3 216
ASP 1  49
 None
 1.37A 3ko0A-1r1a3:
undetectable
3ko0B-1r1a3:
undetectable
3ko0C-1r1a3:
undetectable
3ko0D-1r1a3:
undetectable		 3ko0A-1r1a3:
17.33
3ko0B-1r1a3:
17.33
3ko0C-1r1a3:
17.33
3ko0D-1r1a3:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 11 ASP 1  49
LEU 3 165
SER 3 116
PHE 3 115
CYH 3 216
 None
 1.36A 3ko0C-1r1a1:
undetectable
3ko0D-1r1a1:
undetectable
3ko0E-1r1a1:
undetectable
3ko0F-1r1a1:
undetectable		 3ko0C-1r1a1:
15.95
3ko0D-1r1a1:
15.95
3ko0E-1r1a1:
15.95
3ko0F-1r1a1:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 11 ASP 1  49
LEU 3 165
SER 3 116
PHE 3 115
CYH 3 216
 None
 1.29A 3ko0E-1r1a1:
undetectable
3ko0F-1r1a1:
undetectable
3ko0G-1r1a1:
undetectable
3ko0H-1r1a1:
undetectable		 3ko0E-1r1a1:
15.95
3ko0F-1r1a1:
15.95
3ko0G-1r1a1:
15.95
3ko0H-1r1a1:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RHG_A_BEZA369_0
(PUTATIVE
PHOPHOTRIESTERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A;
Rhinovirus
A) 		5 / 10 LEU 2 184
PHE 2 190
GLU 1  38
ASP 3  50
PHE 3 212
 None
 1.04A 3rhgA-1r1a2:
0.0		 3rhgA-1r1a2:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 6 ARG 1 111
TYR 3 105
PHE 1  70
LEU 1 115
 None
 1.39A 3tgvD-1r1a1:
0.0		 3tgvD-1r1a1:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		4 / 5 ILE 2 225
PRO 2 226
SER 2 157
GLY 2  77
 None
 1.15A 3tkdB-1r1a2:
undetectable		 3tkdB-1r1a2:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		4 / 5 ILE 2 225
PRO 2 226
SER 2 157
GLY 2  77
 None
 1.16A 3tkdA-1r1a2:
undetectable		 3tkdA-1r1a2:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		4 / 6 THR 1 205
ASN 1 204
GLY 1 202
ASP 1 203
 None
 1.04A 3w9tE-1r1a1:
undetectable		 3w9tE-1r1a1:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		4 / 6 THR 1 205
ASN 1 204
GLY 1 202
ASP 1 203
 None
 1.04A 3w9tF-1r1a1:
undetectable		 3w9tF-1r1a1:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 7 THR 3 227
THR 3  92
LEU 2 179
ASN 2 182
 None
 0.99A 4pfjA-1r1a3:
undetectable		 4pfjA-1r1a3:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 8 PHE 1 121
ASP 3  18
ASP 3  17
TYR 1 240
 None
 1.29A 4qb9D-1r1a1:
undetectable		 4qb9D-1r1a1:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A) 		3 / 3 PHE 1 116
THR 3 227
LEU 3  43
 None
 0.78A 4qztA-1r1a1:
0.0		 4qztA-1r1a1:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		4 / 7 ILE 3 189
LEU 3 113
LEU 3  94
ILE 3  53
 None
 0.74A 4rmjA-1r1a3:
undetectable		 4rmjA-1r1a3:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		5 / 12 GLY 1 133
ILE 1 131
LEU 1 231
VAL 1 233
ILE 1 235
 None
 1.12A 4uw0A-1r1a1:
undetectable		 4uw0A-1r1a1:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 9 LEU 2 173
GLY 2 177
ILE 1 278
VAL 1 257
THR 1 276
 None
 1.25A 4x3mA-1r1a2:
undetectable		 4x3mA-1r1a2:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 9 LEU 2 173
GLY 2 177
ILE 1 278
VAL 1 257
THR 1 276
 None
 1.23A 4x3mB-1r1a2:
undetectable		 4x3mB-1r1a2:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 11 ASP 2 170
ALA 1 256
VAL 1 257
TYR 1 267
GLY 3  63
 None
 0.94A 4xnxA-1r1a2:
undetectable		 4xnxA-1r1a2:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		4 / 6 ILE 2  16
PHE 2  63
ARG 2  18
ILE 2 202
 None
 1.32A 4zzcA-1r1a2:
undetectable
4zzcB-1r1a2:
undetectable		 4zzcA-1r1a2:
19.94
4zzcB-1r1a2:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		4 / 4 LEU 1 127
ARG 1 181
ILE 1 171
PHE 1 182
 None
 1.35A 5kirB-1r1a1:
0.0		 5kirB-1r1a1:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		5 / 12 MET 1 143
ILE 1 141
VAL 1 234
ILE 1 131
PRO 1 129
 None
 1.13A 5mlmA-1r1a1:
undetectable		 5mlmA-1r1a1:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 11 LEU 3 165
VAL 3 154
ARG 3 144
ALA 3 132
GLN 3 194
 None
 1.14A 5o96A-1r1a3:
undetectable
5o96B-1r1a3:
undetectable		 5o96A-1r1a3:
21.17
5o96B-1r1a3:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		5 / 12 MET 1 169
ILE 1 171
ILE 1 239
PHE 1 182
THR 1 237
 None
 1.05A 5tiwB-1r1a1:
undetectable		 5tiwB-1r1a1:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 12 VAL 3  55
PHE 3  83
ILE 3  85
ILE 3 189
VAL 3  70
 None
 0.93A 5uvmB-1r1a3:
undetectable		 5uvmB-1r1a3:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		6 / 12 ILE 2 191
LEU 2 222
VAL 2 244
ILE 2 242
LEU 2 184
LEU 2 180
 None
 1.24A 5ycnA-1r1a2:
undetectable		 5ycnA-1r1a2:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A) 		5 / 12 PHE 2 190
LEU 2 222
ILE 2 242
LEU 2 184
LEU 2 180
 None
 1.15A 5ycpA-1r1a2:
undetectable		 5ycpA-1r1a2:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP4)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 5 HIS 1 245
ALA 4  35
SER 4  38
GLY 4  39
 None
 1.27A 5yodB-1r1a1:
undetectable		 5yodB-1r1a1:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A) 		5 / 12 VAL 3  55
GLY 3 187
ALA 3 186
PHE 3 115
VAL 3 213
 None
 1.19A 6bqgA-1r1a3:
undetectable		 6bqgA-1r1a3:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)
(Rhinovirus
A;
Rhinovirus
A) 		5 / 12 ILE 1 239
TRP 1 173
SER 3  21
PHE 1 179
HIS 1 241
 None
None
None
None
SUC  1 288 (-3.9A)
 1.40A 6chgC-1r1a1:
undetectable		 6chgC-1r1a1:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
(Rhinovirus
A) 		5 / 12 ARG 1 158
VAL 1  84
ILE 1 235
VAL 1 142
ILE 1 141
 None
 1.30A 6gsdA-1r1a1:
undetectable		 6gsdA-1r1a1:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 7 ASP 2 212
TYR 1 194
GLU 2 129
ASP 1 198
 None
 1.31A 6mn5B-1r1a2:
undetectable		 6mn5B-1r1a2:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
A;
Rhinovirus
A) 		4 / 6 ASP 2 212
TYR 1 194
GLU 2 129
ASP 1 198
 None
 1.30A 6mn5C-1r1a2:
undetectable		 6mn5C-1r1a2:
16.33