SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 LEU D 491
LEU A 419
ALA A 415
ILE D 298
THR D 468
 None
 1.15A 1crbA-1r20D:
undetectable		 1crbA-1r20D:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU D 491
ALA A 415
ILE D 298
ILE D 443
 None
 1.02A 1crbA-1r20D:
undetectable		 1crbA-1r20D:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU D 491
LEU A 419
ALA A 415
ILE D 298
 None
 0.96A 1crbA-1r20D:
undetectable		 1crbA-1r20D:
18.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.75A 1fm6A-1r20A:
23.6		 1fm6A-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 ARG A 297
LEU A 325
VAL A 341
HIS A 434
LEU A 435
 None
None
EPH  A4000 (-4.9A)
None
EPH  A4000 ( 4.6A)
 0.77A 1fm6U-1r20A:
23.7		 1fm6U-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 ARG A 297
VAL A 341
ILE A 344
HIS A 434
LEU A 435
 None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.1A)
None
EPH  A4000 ( 4.6A)
 0.85A 1fm6U-1r20A:
23.7		 1fm6U-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		6 / 12 TRP A 286
LEU A 290
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.94A 1fm9A-1r20A:
23.8		 1fm9A-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.73A 1k74A-1r20A:
23.8		 1k74A-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.79A 1k74A-1r20A:
23.8		 1k74A-1r20A:
46.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.73A 1xdkA-1r20A:
24.4		 1xdkA-1r20A:
45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.72A 1xdkE-1r20A:
24.4		 1xdkE-1r20A:
45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.61A 1xlsA-1r20A:
23.7		 1xlsA-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.68A 1xlsA-1r20A:
23.7		 1xlsA-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.61A 1xlsB-1r20A:
23.6		 1xlsB-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.70A 1xlsB-1r20A:
23.6		 1xlsB-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.60A 1xlsC-1r20A:
23.6		 1xlsC-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.69A 1xlsC-1r20A:
23.6		 1xlsC-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.61A 1xlsD-1r20A:
23.6		 1xlsD-1r20A:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.69A 1xlsD-1r20A:
23.6		 1xlsD-1r20A:
46.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		4 / 6 TYR D 308
GLY D 359
PHE D 360
SER D 361
 None
 1.10A 2a3cA-1r20D:
undetectable		 2a3cA-1r20D:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		4 / 6 TYR D 308
GLY D 359
PHE D 360
SER D 361
 None
 1.09A 2a3cB-1r20D:
undetectable		 2a3cB-1r20D:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 9 LEU A 399
LEU A 369
ARG A 420
LEU A 421
ALA A 416
 None
 0.92A 2bxeA-1r20A:
undetectable		 2bxeA-1r20A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 10 LEU A 399
LEU A 369
ARG A 420
LEU A 421
ALA A 416
 None
 0.91A 2bxeB-1r20A:
undetectable		 2bxeB-1r20A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
ARG A 297
ILE A 344
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 0.80A 2jfaA-1r20A:
21.6		 2jfaA-1r20A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		4 / 6 ARG D 387
ASN D 400
ASN D 504
LEU D 522
 None
None
HWG  D2000 (-3.0A)
None
 1.26A 2nyrA-1r20D:
undetectable		 2nyrA-1r20D:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
ARG A 297
ILE A 344
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 0.79A 2qxsA-1r20A:
23.4		 2qxsA-1r20A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
ARG A 297
ILE A 344
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 0.78A 2qxsB-1r20A:
23.4		 2qxsB-1r20A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 10 ALA A 371
ALA A 368
LEU A 417
MET A 356
VAL A 361
 None
 1.34A 2wuzA-1r20A:
undetectable		 2wuzA-1r20A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 10 ALA A 371
ALA A 368
LEU A 417
MET A 356
VAL A 361
 None
 1.32A 2wuzB-1r20A:
undetectable		 2wuzB-1r20A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 6 LEU A 325
GLY A 328
LEU A 249
SER A 248
 None
None
EPH  A4000 (-4.4A)
None
 0.92A 3aiaA-1r20A:
undetectable		 3aiaA-1r20A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 ARG A 297
LEU A 325
VAL A 341
HIS A 434
LEU A 435
 None
None
EPH  A4000 (-4.9A)
None
EPH  A4000 ( 4.6A)
 0.91A 3dzuA-1r20A:
24.2		 3dzuA-1r20A:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 ASN A 287
LEU A 325
VAL A 341
HIS A 434
LEU A 435
 None
None
EPH  A4000 (-4.9A)
None
EPH  A4000 ( 4.6A)
 0.89A 3dzuA-1r20A:
24.2		 3dzuA-1r20A:
26.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		8 / 12 GLN A 256
TRP A 286
LEU A 290
ARG A 297
LEU A 325
VAL A 341
ILE A 344
LEU A 435
 None
None
EPH  A4000 ( 4.8A)
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 1.04A 3h0aA-1r20A:
23.1		 3h0aA-1r20A:
45.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 LEU A 249
GLY A 253
GLN A 256
TRP A 286
ARG A 297
 EPH  A4000 (-4.4A)
EPH  A4000 ( 4.4A)
None
None
None
 0.91A 3h52C-1r20A:
19.2		 3h52C-1r20A:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 6 VAL A 441
SER A 428
LEU A 331
LEU A 230
 None
None
EPH  A4000 (-4.5A)
EPH  A4000 (-4.7A)
 0.98A 3kk6A-1r20A:
undetectable		 3kk6A-1r20A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		5 / 12 ALA D 402
GLU D 341
LEU D 345
LEU D 522
TYR D 408
 None
 1.12A 4ej1B-1r20D:
undetectable		 4ej1B-1r20D:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 6 PHE A 396
PHE A 414
ALA A 368
LEU A 421
 None
 1.05A 4ejgD-1r20A:
undetectable		 4ejgD-1r20A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		5 / 12 LEU D 439
ILE D 298
ALA D 299
GLY D 307
ALA D 438
 None
 0.71A 4enhA-1r20D:
undetectable		 4enhA-1r20D:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		4 / 5 THR D 441
LEU D 382
THR D 499
MET D 502
 None
 1.39A 4mbsB-1r20D:
undetectable		 4mbsB-1r20D:
20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 11 ARG A 297
LEU A 325
VAL A 341
HIS A 434
LEU A 435
 None
None
EPH  A4000 (-4.9A)
None
EPH  A4000 ( 4.6A)
 0.86A 4nqaA-1r20A:
22.9		 4nqaA-1r20A:
33.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		3 / 3 LEU D 421
MET D 381
TYR D 428
 None
HWG  D2000 ( 4.2A)
None
 0.70A 4p6xG-1r20D:
20.9		 4p6xG-1r20D:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		3 / 3 PRO D 519
LEU D 522
GLN D 348
 None
 0.71A 4pevB-1r20D:
undetectable		 4pevB-1r20D:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
ARG A 297
ILE A 344
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 0.76A 4xi3B-1r20A:
23.5		 4xi3B-1r20A:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 6 LEU A 337
ILE A 344
HIS A 434
PRO A 245
 None
EPH  A4000 ( 4.1A)
None
None
 1.08A 4xi3C-1r20A:
23.5		 4xi3C-1r20A:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 1r20 ECDYSONE RECEPTOR
ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 9 ALA A 415
ASP A 400
GLY D 488
LEU D 491
LEU D 466
 None
 1.03A 5dqfA-1r20A:
undetectable		 5dqfA-1r20A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU D 491
ALA A 415
ILE D 298
ILE D 443
 None
 1.00A 5h8tA-1r20D:
undetectable		 5h8tA-1r20D:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU A 419
ALA A 415
ILE D 298
ILE D 443
 None
 1.10A 5hbsA-1r20D:
undetectable		 5hbsA-1r20D:
17.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 11 GLN A 256
TRP A 286
LEU A 290
ARG A 297
LEU A 435
 None
None
EPH  A4000 ( 4.8A)
None
EPH  A4000 ( 4.6A)
 1.20A 5ji0A-1r20A:
24.0		 5ji0A-1r20A:
45.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		6 / 11 TRP A 286
LEU A 290
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.84A 5ji0A-1r20A:
24.0		 5ji0A-1r20A:
45.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU D 491
LEU A 419
ALA A 415
ILE D 443
 None
 0.79A 5ljeA-1r20D:
undetectable		 5ljeA-1r20D:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1r20 ULTRASPIRACLE
PROTEIN
ECDYSONE RECEPTOR
(Heliothis
virescens;
Heliothis
virescens) 		5 / 12 PHE D 487
LEU D 491
LEU A 419
ALA A 415
TYR D 465
 None
 0.94A 5ljeA-1r20D:
undetectable		 5ljeA-1r20D:
20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.59A 5uanA-1r20A:
24.2		 5uanA-1r20A:
33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.66A 5z12B-1r20A:
24.3		 5z12B-1r20A:
40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
LEU A 290
ARG A 297
LEU A 325
LEU A 435
 None
EPH  A4000 ( 4.8A)
None
None
EPH  A4000 ( 4.6A)
 0.98A 5z12B-1r20A:
24.3		 5z12B-1r20A:
40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
VAL A 341
LEU A 435
 None
None
None
EPH  A4000 (-4.9A)
EPH  A4000 ( 4.6A)
 0.74A 5z12C-1r20A:
23.8		 5z12C-1r20A:
40.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 TRP A 286
ARG A 297
LEU A 325
ILE A 344
LEU A 435
 None
None
None
EPH  A4000 ( 4.1A)
EPH  A4000 ( 4.6A)
 0.94A 6a5yD-1r20A:
24.6		 6a5yD-1r20A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		5 / 12 ARG A 297
LEU A 325
ILE A 344
HIS A 434
LEU A 435
 None
None
EPH  A4000 ( 4.1A)
None
EPH  A4000 ( 4.6A)
 0.77A 6a5zL-1r20A:
24.3		 6a5zL-1r20A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1r20 ECDYSONE RECEPTOR
(Heliothis
virescens) 		3 / 3 GLY D 492
THR D 495
GLU D 496
 None
 0.65A 6b58A-1r20D:
undetectable		 6b58A-1r20D:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		3 / 3 LEU A 208
ASN A 376
LEU A 273
 None
 0.66A 6exiA-1r20A:
undetectable		 6exiA-1r20A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 7 GLN A 256
GLY A 253
PHE A 229
VAL A 441
 None
EPH  A4000 ( 4.4A)
None
None
 1.07A 6hu9S-1r20A:
undetectable
6hu9q-1r20A:
undetectable		 6hu9S-1r20A:
18.67
6hu9q-1r20A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1r20 ULTRASPIRACLE
PROTEIN
(Heliothis
virescens) 		4 / 5 LEU A 230
GLN A 228
PHE A 229
PHE A 436
 EPH  A4000 (-4.7A)
None
None
None
 1.27A 6nmpP-1r20A:
undetectable
6nmpW-1r20A:
0.0		 6nmpP-1r20A:
20.91
6nmpW-1r20A:
13.30