SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		4 / 8 VAL B  48
THR B  97
TYR B  94
LEU B  81
 None
 1.00A 1z2bB-1r24B:
undetectable		 1z2bB-1r24B:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		4 / 6 GLY B  54
GLY B  33
MET B  34
ASN B  74
 None
 0.95A 3e9rA-1r24B:
undetectable		 3e9rA-1r24B:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		4 / 6 GLY B  54
GLY B  33
MET B  34
ASN B  74
 None
 0.96A 3e9rC-1r24B:
undetectable		 3e9rC-1r24B:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		4 / 5 TYR B  94
LEU B  81
LEU B  86
ARG B  67
 None
 1.24A 4em2A-1r24B:
undetectable		 4em2A-1r24B:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		5 / 11 PRO B 132
VAL B 130
SER B 188
SER B 187
GLY B 148
 None
 1.31A 4mmaA-1r24B:
undetectable		 4mmaA-1r24B:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		3 / 3 SER B 211
ALA B 207
VAL B 206
 None
 0.54A 5xiwC-1r24B:
undetectable		 5xiwC-1r24B:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		3 / 3 PHE B  68
ARG B  87
ALA B  40
 None
 0.80A 6ecfB-1r24B:
undetectable		 6ecfB-1r24B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		3 / 3 PHE B  68
ARG B  87
ALA B  92
 None
 0.95A 6ecfB-1r24B:
undetectable		 6ecfB-1r24B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))
(Mus
musculus) 		4 / 6 ALA B  24
SER B  30
GLY B  54
ILE B  70
 None
 0.83A 6f8cA-1r24B:
undetectable		 6f8cA-1r24B:
18.68