SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 ALA A 192
VAL A 141
TRP A 142
 None
None
FAD  A 399 (-4.5A)
 0.78A 1bdwA-1r2jA:
undetectable
1bdwB-1r2jA:
undetectable		 1bdwA-1r2jA:
3.96
1bdwB-1r2jA:
3.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 5 ALA A 316
ALA A 340
LYS A 341
GLU A 344
 None
 0.82A 1e7cA-1r2jA:
0.0		 1e7cA-1r2jA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 11 SER A 228
VAL A 229
GLY A 225
GLY A 232
HIS A 191
 None
None
None
None
FAD  A 399 (-4.1A)
 1.29A 1iolA-1r2jA:
undetectable		 1iolA-1r2jA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLY A 225
VAL A 229
ALA A 220
MET A  80
GLY A 348
 None
 1.06A 1kiaA-1r2jA:
undetectable		 1kiaA-1r2jA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLY A 225
VAL A 229
ALA A 220
MET A  80
GLY A 348
 None
 1.05A 1kiaB-1r2jA:
undetectable		 1kiaB-1r2jA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLY A 225
VAL A 229
ALA A 220
MET A  80
GLY A 348
 None
 1.05A 1kiaC-1r2jA:
undetectable		 1kiaC-1r2jA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLY A 225
VAL A 229
ALA A 220
MET A  80
GLY A 348
 None
 1.03A 1nbhB-1r2jA:
undetectable		 1nbhB-1r2jA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 THR A  76
GLY A 232
VAL A  64
ALA A 308
ALA A 307
 None
 1.31A 1nw5A-1r2jA:
undetectable		 1nw5A-1r2jA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 5 ARG A 338
ASP A  20
GLU A 334
LYS A 330
 None
 1.19A 2xrzA-1r2jA:
undetectable
2xrzB-1r2jA:
undetectable		 2xrzA-1r2jA:
22.95
2xrzB-1r2jA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 LEU A 217
GLY A  89
GLY A 209
SER A 210
LEU A 207
 None
 1.10A 3e23A-1r2jA:
undetectable		 3e23A-1r2jA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 8 LEU A  71
ARG A  72
ALA A  62
GLY A  13
 None
 0.92A 3ny4A-1r2jA:
undetectable		 3ny4A-1r2jA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 10 ARG A 241
GLY A 235
ALA A 279
VAL A 234
GLU A 275
 None
 1.26A 4da7A-1r2jA:
undetectable		 4da7A-1r2jA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 7 ALA A 107
ASP A 150
VAL A 167
THR A  84
 None
 0.97A 4eyrA-1r2jA:
undetectable		 4eyrA-1r2jA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 7 ARG A  72
THR A  61
TYR A 224
GLY A 225
 None
 1.13A 5hwaA-1r2jA:
undetectable		 5hwaA-1r2jA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.56A 5qglA-1r2jA:
undetectable		 5qglA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.64A 5qgnA-1r2jA:
undetectable		 5qgnA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.66A 5qguA-1r2jA:
undetectable		 5qguA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qgvA-1r2jA:
undetectable		 5qgvA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.67A 5qgwA-1r2jA:
undetectable		 5qgwA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qgxA-1r2jA:
undetectable		 5qgxA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.64A 5qgyA-1r2jA:
undetectable		 5qgyA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.67A 5qgzA-1r2jA:
undetectable		 5qgzA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qh0A-1r2jA:
undetectable		 5qh0A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.63A 5qh1A-1r2jA:
undetectable		 5qh1A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qh2A-1r2jA:
undetectable		 5qh2A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.66A 5qh3A-1r2jA:
undetectable		 5qh3A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.64A 5qh4A-1r2jA:
undetectable		 5qh4A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qh5A-1r2jA:
undetectable		 5qh5A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.66A 5qh7A-1r2jA:
undetectable		 5qh7A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.70A 5qh9A-1r2jA:
undetectable		 5qh9A-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.61A 5qhcA-1r2jA:
undetectable		 5qhcA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.65A 5qheA-1r2jA:
undetectable		 5qheA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.70A 5qhfA-1r2jA:
undetectable		 5qhfA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.63A 5qhgA-1r2jA:
undetectable		 5qhgA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 VAL A 153
VAL A 167
GLN A  93
 None
 0.67A 5qhhA-1r2jA:
undetectable		 5qhhA-1r2jA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLU A  42
GLY A  51
VAL A  64
GLY A  58
SER A  54
 None
 1.16A 5vooC-1r2jA:
undetectable		 5vooC-1r2jA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 12 GLU A  42
GLY A  51
VAL A  64
GLY A  58
SER A  54
 None
 1.12A 5vopB-1r2jA:
undetectable		 5vopB-1r2jA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 4 VAL A  12
LEU A   8
LEU A   7
ASP A  36
 None
 1.31A 5xv7A-1r2jA:
1.1		 5xv7A-1r2jA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 8 ILE A 301
LEU A 362
ALA A 363
LEU A 364
 None
 0.72A 5y7pC-1r2jA:
0.0		 5y7pC-1r2jA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		4 / 8 ILE A 301
LEU A 362
ALA A 363
LEU A 364
 None
 0.66A 5y7pE-1r2jA:
undetectable		 5y7pE-1r2jA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		3 / 3 TYR A 148
PRO A  26
LEU A  29
 None
 0.94A 6beoA-1r2jA:
undetectable		 6beoA-1r2jA:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 1r2j PROTEIN FKBI
(Streptomyces
hygroscopicus) 		5 / 11 GLU A 347
SER A  73
ARG A  72
ALA A 189
ALA A 239
 None
 1.46A 6efnA-1r2jA:
undetectable		 6efnA-1r2jA:
22.89