SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 4 GLY A  94
LEU A  92
GLY A 119
ARG A  95
 None
 1.13A 1j7kA-1r3dA:
0.0		 1j7kA-1r3dA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGL_L_ESTL911_1
(IG GAMMA-1-CHAIN
IG KAPPA-CHAIN)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 10 GLN A  32
ALA A  45
LEU A  20
HIS A   7
PHE A   8
 None
 1.38A 1jglH-1r3dA:
undetectable
1jglL-1r3dA:
undetectable		 1jglH-1r3dA:
19.64
1jglL-1r3dA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 GLY A  23
SER A  91
TYR A 156
HIS A 240
 None
 1.04A 1maaD-1r3dA:
11.5		 1maaD-1r3dA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 10 ASP A  49
TRP A  31
GLY A  94
GLY A  93
SER A  91
 None
 1.17A 1w76B-1r3dA:
11.0		 1w76B-1r3dA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		3 / 3 SER A 163
GLU A 117
ASP A  30
 None
 0.82A 2avdB-1r3dA:
2.6		 2avdB-1r3dA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		3 / 3 HIS A  22
ILE A  71
LEU A  46
 None
 0.77A 2kceA-1r3dA:
undetectable		 2kceA-1r3dA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 12 ILE A  86
ALA A  77
VAL A  18
LEU A  46
LEU A   6
 None
 0.92A 2yqzA-1r3dA:
undetectable		 2yqzA-1r3dA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 12 ILE A  86
ALA A  77
VAL A  18
LEU A  46
LEU A   6
 None
 0.94A 2yqzB-1r3dA:
undetectable		 2yqzB-1r3dA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 6 THR A  74
LEU A  48
VAL A  21
VAL A  85
 None
 1.09A 2zuhA-1r3dA:
0.0		 2zuhA-1r3dA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 10 VAL A  75
GLN A  73
LEU A 111
VAL A  85
LEU A  87
 None
 1.03A 3gwxA-1r3dA:
0.0		 3gwxA-1r3dA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 LEU A 152
SER A 153
LEU A 188
ILE A 148
 None
 0.94A 3ln1A-1r3dA:
undetectable		 3ln1A-1r3dA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 7 LEU A 152
SER A 153
LEU A 188
ILE A 148
 None
 0.95A 3ln1B-1r3dA:
undetectable		 3ln1B-1r3dA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 PRO A 209
MET A 257
SER A 260
ILE A 261
 None
 0.73A 3sfeB-1r3dA:
undetectable
3sfeC-1r3dA:
undetectable		 3sfeB-1r3dA:
20.14
3sfeC-1r3dA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 THR A  74
LEU A  48
VAL A  21
VAL A  85
 None
 1.05A 4l4dA-1r3dA:
0.0		 4l4dA-1r3dA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 12 ILE A 253
ILE A  71
LEU A  50
GLY A  94
ILE A  97
 None
 1.19A 4o1eB-1r3dA:
3.5		 4o1eB-1r3dA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 9 SER A   3
THR A  74
VAL A  19
VAL A  21
LEU A  46
 None
 1.46A 4wnvA-1r3dA:
2.1		 4wnvA-1r3dA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		5 / 12 ILE A  71
LEU A  96
VAL A  19
VAL A  85
LEU A 111
 None
 1.01A 4y0qA-1r3dA:
undetectable		 4y0qA-1r3dA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 5 VAL A 213
VAL A  88
GLY A  89
PHE A 250
 None
 0.95A 5d4nA-1r3dA:
undetectable
5d4nC-1r3dA:
undetectable		 5d4nA-1r3dA:
17.05
5d4nC-1r3dA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 ARG A 132
GLU A 125
GLU A 128
GLY A 122
 None
 1.00A 5sxqA-1r3dA:
undetectable		 5sxqA-1r3dA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 ARG A 132
GLU A 125
GLU A 128
GLY A 122
 None
 0.99A 5sxtA-1r3dA:
undetectable		 5sxtA-1r3dA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 8 ARG A 132
GLU A 125
GLU A 128
GLY A 122
 None
 0.96A 5sxtB-1r3dA:
undetectable		 5sxtB-1r3dA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 6 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.91A 6e43A-1r3dA:
undetectable		 6e43A-1r3dA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 6 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.92A 6e43B-1r3dA:
undetectable		 6e43B-1r3dA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 6 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.90A 6e43C-1r3dA:
undetectable		 6e43C-1r3dA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974
(Vibrio
cholerae) 		4 / 6 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.91A 6e43D-1r3dA:
undetectable		 6e43D-1r3dA:
23.27