SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		5 / 7 SER A 174
SER A 176
ARG A 185
GLN A 211
GLU A 213
 None
 0.91A 2c8aA-1r45A:
30.7		 2c8aA-1r45A:
63.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		4 / 7 GLY A 129
SER A 174
ARG A 185
GLU A 213
 None
 0.80A 2c8aB-1r45A:
30.3		 2c8aB-1r45A:
63.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		4 / 6 SER A 174
SER A 176
ARG A 185
GLU A 213
 None
 1.02A 2c8aC-1r45A:
29.8		 2c8aC-1r45A:
63.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		4 / 7 GLY A 129
SER A 174
ARG A 185
GLU A 213
 None
 0.97A 2c8aD-1r45A:
30.3		 2c8aD-1r45A:
63.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		3 / 3 ARG A 167
GLY A 136
PRO A 137
 SO4  A1003 (-4.0A)
None
None
 0.75A 2hreD-1r45A:
0.0		 2hreD-1r45A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		4 / 6 LEU A 212
ILE A 173
THR A 175
MET A 120
 None
 1.35A 5ljeA-1r45A:
undetectable		 5ljeA-1r45A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1r45 MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
phage
c-st) 		3 / 3 LEU A 216
ASP A 166
ILE A 224
 None
 0.55A 6dh0B-1r45A:
undetectable		 6dh0B-1r45A:
16.58