SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r4t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 1r4t EXOENZYME S
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 152
LEU A 148
LEU A 145
ALA A 144
ALA A 124
 None
 1.00A 4fn9A-1r4tA:
undetectable		 4fn9A-1r4tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 1r4t EXOENZYME S
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 151
LEU A 123
ILE A 176
LEU A 210
LEU A 172
 None
 1.19A 4j24D-1r4tA:
undetectable		 4j24D-1r4tA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r4t EXOENZYME S
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 195
LEU A 202
GLY A 130
ALA A 132
 None
 0.73A 5f1aA-1r4tA:
undetectable		 5f1aA-1r4tA:
14.86