SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 ASN A  11
ILE A  71
LEU A  56
VAL A  60
HIS A  63
 None
 1.22A 4azsA-1r57A:
undetectable		 4azsA-1r57A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 HIS A 100
ASP A  90
TYR A  92
HIS A 102
 None
 1.50A 5x19N-1r57A:
undetectable
5x19P-1r57A:
undetectable		 5x19N-1r57A:
10.87
5x19P-1r57A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A  71
GLU A  66
HIS A  63
VAL A  60
 None
 1.19A 6j20A-1r57A:
undetectable		 6j20A-1r57A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 HIS A 100
ASP A  90
TYR A  92
HIS A 102
 None
 1.47A 6nmfN-1r57A:
undetectable
6nmfP-1r57A:
undetectable		 6nmfN-1r57A:
10.87
6nmfP-1r57A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 HIS A 100
ASP A  90
TYR A  92
HIS A 102
 None
 1.48A 6nmpA-1r57A:
undetectable
6nmpC-1r57A:
undetectable		 6nmpA-1r57A:
10.87
6nmpC-1r57A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1r57 CONSERVED
HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 HIS A 100
ASP A  90
TYR A  92
HIS A 102
 None
 1.49A 6nmpN-1r57A:
undetectable
6nmpP-1r57A:
undetectable		 6nmpN-1r57A:
10.87
6nmpP-1r57A:
16.05