SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1r5t CYTIDINE DEAMINASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  97
LEU A 132
LEU A 131
MET A 128
MET A  67
 None
 1.03A 1mx1F-1r5tA:
undetectable		 1mx1F-1r5tA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1r5t CYTIDINE DEAMINASE
(Saccharomyces
cerevisiae) 		4 / 8 GLU A  52
SER A  30
VAL A  98
CYH A  96
 None
None
None
ZN  A 150 (-2.2A)
 1.20A 3b9lA-1r5tA:
undetectable		 3b9lA-1r5tA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1r5t CYTIDINE DEAMINASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  52
VAL A  51
CYH A  59
 None
 1.03A 3fbxA-1r5tA:
0.4		 3fbxA-1r5tA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1r5t CYTIDINE DEAMINASE
(Saccharomyces
cerevisiae) 		5 / 12 PRO A  95
GLU A  63
MET A 115
ALA A  21
LEU A  19
 None
ZN  A 150 ( 4.0A)
None
None
None
 1.08A 4oadA-1r5tA:
undetectable		 4oadA-1r5tA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1r5t CYTIDINE DEAMINASE
(Saccharomyces
cerevisiae) 		3 / 3 LEU A  39
PHE A 111
ILE A  38
 None
 0.68A 5dzk1-1r5tA:
undetectable
5dzkF-1r5tA:
undetectable
5dzkM-1r5tA:
undetectable		 5dzk1-1r5tA:
1.52
5dzkF-1r5tA:
20.89
5dzkM-1r5tA:
23.65