SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1r62 NITROGEN REGULATION
PROTEIN NR(II)
(Escherichia
coli) 		3 / 3 LEU A 243
VAL A 246
LEU A 250
 None
 0.51A 1mz9B-1r62A:
undetectable		 1mz9B-1r62A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1r62 NITROGEN REGULATION
PROTEIN NR(II)
(Escherichia
coli) 		4 / 8 GLY A 257
VAL A 218
LEU A 250
PRO A 215
 None
 1.12A 3bgdB-1r62A:
undetectable		 3bgdB-1r62A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1r62 NITROGEN REGULATION
PROTEIN NR(II)
(Escherichia
coli) 		3 / 3 TYR A 344
ASP A 284
ASP A 225
 None
 0.62A 4a6eA-1r62A:
undetectable		 4a6eA-1r62A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r62 NITROGEN REGULATION
PROTEIN NR(II)
(Escherichia
coli) 		4 / 5 ARG A 222
VAL A 210
LEU A 214
SER A 211
 None
 1.26A 4e1gA-1r62A:
undetectable		 4e1gA-1r62A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1r62 NITROGEN REGULATION
PROTEIN NR(II)
(Escherichia
coli) 		5 / 10 VAL A 343
TYR A 344
VAL A 241
ILE A 238
LEU A 228
 None
 1.40A 4jtqA-1r62A:
undetectable		 4jtqA-1r62A:
17.07