SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ARG A  57
ASP A 255
GLY A  44
ILE A  45
 SO4  A 905 (-3.6A)
None
None
None
 0.71A 1d4sB-1r6aA:
undetectable		 1d4sB-1r6aA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
ARG A 163
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
None
None
 1.32A 1eizA-1r6aA:
14.7		 1eizA-1r6aA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
None
 0.61A 1ej0A-1r6aA:
13.1		 1ej0A-1r6aA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 GLY A 102
LEU A 103
THR A 104
VAL A  78
 None
None
SAH  A 887 (-4.5A)
None
 1.11A 1ekjF-1r6aA:
undetectable
1ekjG-1r6aA:
2.0		 1ekjF-1r6aA:
21.50
1ekjG-1r6aA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 THR A 176
LEU A 143
LEU A 103
GLN A 127
 None
 0.96A 1fbmA-1r6aA:
undetectable		 1fbmA-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.69A 1fbmB-1r6aA:
undetectable		 1fbmB-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.69A 1fbmD-1r6aA:
undetectable		 1fbmD-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 5 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.68A 1fbmE-1r6aA:
undetectable		 1fbmE-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 5 THR A 176
LEU A 143
VAL A  78
LEU A 103
GLN A 127
 None
 0.92A 1fbmE-1r6aA:
undetectable		 1fbmE-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 GLY A 120
LEU A 123
GLY A  93
ARG A 263
 None
 1.29A 1j7kA-1r6aA:
undetectable		 1j7kA-1r6aA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 GLY A  86
SER A  56
LEU A 126
ILE A 114
 SAH  A 887 (-3.3A)
SAH  A 887 ( 2.8A)
None
None
 0.96A 1yajF-1r6aA:
undetectable		 1yajF-1r6aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 7 LEU A 239
GLY A  10
THR A   8
ILE A 191
 None
 0.94A 2bdmA-1r6aA:
undetectable		 2bdmA-1r6aA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 SER A 211
ARG A 207
LEU A 205
HIS A 216
 None
 1.32A 2f8dA-1r6aA:
0.4		 2f8dA-1r6aA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
VAL A 132
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.5A)
None
 0.72A 2nyuA-1r6aA:
14.1		 2nyuA-1r6aA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
VAL A 132
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.5A)
None
 0.70A 2nyuB-1r6aA:
14.1		 2nyuB-1r6aA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 8 ARG A  57
ASP A 255
GLY A  44
ILE A  45
 SO4  A 905 (-3.6A)
None
None
None
 0.73A 2o4nB-1r6aA:
undetectable		 2o4nB-1r6aA:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 (-3.9A)
 0.33A 2oxtA-1r6aA:
39.3		 2oxtA-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
 0.59A 2oxtA-1r6aA:
39.3		 2oxtA-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 SER A  56
HIS A 110
ASP A 131
 SAH  A 887 ( 2.8A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
 0.47A 2oxtA-1r6aA:
39.3		 2oxtA-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
 0.62A 2oxtB-1r6aA:
39.4		 2oxtB-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
LYS A 181
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
 0.55A 2oxtB-1r6aA:
39.4		 2oxtB-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.3A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.46A 2oxtB-1r6aA:
39.4		 2oxtB-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 (-3.9A)
None
 0.55A 2oxtC-1r6aA:
38.9		 2oxtC-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 SER A  56
GLY A  58
HIS A 110
ASP A 131
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
 0.66A 2oxtC-1r6aA:
38.9		 2oxtC-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 ASP A  79
GLY A  81
GLY A  85
HIS A 110
GLU A 111
ASP A 146
 SAH  A 887 ( 4.8A)
SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 (-3.9A)
 1.16A 2oxtD-1r6aA:
39.1		 2oxtD-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
ASP A  79
GLY A  81
GLY A  83
GLY A  86
THR A 104
HIS A 110
GLU A 111
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 ( 4.8A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 (-3.9A)
 0.43A 2oxtD-1r6aA:
39.1		 2oxtD-1r6aA:
48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.33A 2pxcA-1r6aA:
40.0		 2pxcA-1r6aA:
60.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.63A 2pxcA-1r6aA:
40.0		 2pxcA-1r6aA:
60.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.41A 2wa2A-1r6aA:
33.2		 2wa2A-1r6aA:
47.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.33A 2wa2B-1r6aA:
39.9		 2wa2B-1r6aA:
47.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LYS A 181
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
None
 0.69A 3douA-1r6aA:
13.8		 3douA-1r6aA:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.1A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.46A 3eluA-1r6aA:
38.9		 3eluA-1r6aA:
52.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.1A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.44A 3elwA-1r6aA:
39.8		 3elwA-1r6aA:
52.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.43A 3embA-1r6aA:
39.0		 3embA-1r6aA:
52.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.39A 3gczA-1r6aA:
39.9		 3gczA-1r6aA:
54.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.64A 3p97A-1r6aA:
41.8		 3p97A-1r6aA:
75.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
 0.84A 3p97A-1r6aA:
41.8		 3p97A-1r6aA:
75.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.55A 3p97C-1r6aA:
41.8		 3p97C-1r6aA:
75.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		7 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.64A 4b17A-1r6aA:
5.9		 4b17A-1r6aA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		5 / 12 ASP A  79
GLY A  83
GLY A  86
HIS A 110
ASP A 146
 SAH  A 887 ( 4.8A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.9A)
 1.01A 4blvB-1r6aA:
7.8		 4blvB-1r6aA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ARG A  38
GLU A 253
LEU A 210
ASP A 255
 SO4  A 903 (-3.8A)
SO4  A 907 ( 4.7A)
None
None
 1.28A 4cevA-1r6aA:
undetectable
4cevB-1r6aA:
undetectable		 4cevA-1r6aA:
20.69
4cevB-1r6aA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ASP A 255
ARG A  38
GLU A 253
LEU A 210
 None
SO4  A 903 (-3.8A)
SO4  A 907 ( 4.7A)
None
 1.30A 4cevA-1r6aA:
undetectable
4cevC-1r6aA:
undetectable		 4cevA-1r6aA:
20.69
4cevC-1r6aA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ARG A  38
GLU A 253
LEU A 210
ASP A 255
 SO4  A 903 (-3.8A)
SO4  A 907 ( 4.7A)
None
None
 1.30A 4cevD-1r6aA:
undetectable
4cevE-1r6aA:
undetectable		 4cevD-1r6aA:
20.69
4cevE-1r6aA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 ARG A  38
GLU A 253
LEU A 210
ASP A 255
 SO4  A 903 (-3.8A)
SO4  A 907 ( 4.7A)
None
None
 1.31A 4cevE-1r6aA:
1.3
4cevF-1r6aA:
1.4		 4cevE-1r6aA:
20.69
4cevF-1r6aA:
20.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.58A 4ctjA-1r6aA:
41.9		 4ctjA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.41A 4ctjC-1r6aA:
41.8		 4ctjC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.58A 4ctkA-1r6aA:
41.8		 4ctkA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
 1.14A 4ctkA-1r6aA:
41.8		 4ctkA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.23A 4ctkC-1r6aA:
41.7		 4ctkC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.66A 4ctkC-1r6aA:
41.7		 4ctkC-1r6aA:
75.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		3 / 3 SER A  56
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.70A 4uckA-1r6aA:
9.0		 4uckA-1r6aA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 6 SER A  56
GLY A  81
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.6A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.66A 4uckB-1r6aA:
9.2		 4uckB-1r6aA:
18.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.28A 5e9qA-1r6aA:
41.5		 5e9qA-1r6aA:
77.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.66A 5e9qA-1r6aA:
41.5		 5e9qA-1r6aA:
77.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.29A 5e9qC-1r6aA:
41.8		 5e9qC-1r6aA:
77.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.77A 5e9qC-1r6aA:
41.8		 5e9qC-1r6aA:
77.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
 1.03A 5e9qC-1r6aA:
41.8		 5e9qC-1r6aA:
77.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
 0.81A 5ec8A-1r6aA:
41.4		 5ec8A-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.28A 5ec8A-1r6aA:
41.4		 5ec8A-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 SER A  56
GLY A  58
GLY A  83
GLY A  86
LYS A 105
GLU A 111
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SO4  A 902 (-2.7A)
None
 1.36A 5ec8A-1r6aA:
41.4		 5ec8A-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.29A 5ec8C-1r6aA:
41.3		 5ec8C-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.61A 5ehgA-1r6aA:
41.6		 5ehgA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.41A 5ehgC-1r6aA:
41.7		 5ehgC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
 0.97A 5ehgC-1r6aA:
41.7		 5ehgC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.29A 5ehiA-1r6aA:
41.6		 5ehiA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.60A 5ehiA-1r6aA:
41.6		 5ehiA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.35A 5ehiC-1r6aA:
42.0		 5ehiC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.59A 5eifA-1r6aA:
41.8		 5eifA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.37A 5eifC-1r6aA:
41.8		 5eifC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.34A 5eiwA-1r6aA:
41.8		 5eiwA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.65A 5eiwA-1r6aA:
41.8		 5eiwA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.25A 5eiwC-1r6aA:
41.7		 5eiwC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.57A 5eiwC-1r6aA:
41.7		 5eiwC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
 0.97A 5eiwC-1r6aA:
41.7		 5eiwC-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.71A 5ekxA-1r6aA:
41.8		 5ekxA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 ( 2.8A)
SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.27A 5ekxA-1r6aA:
41.8		 5ekxA-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.78A 5ekxB-1r6aA:
41.8		 5ekxB-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  81
GLY A  85
HIS A 110
GLU A 111
ASP A 146
ILE A 147
 SAH  A 887 (-3.6A)
SAH  A 887 ( 4.3A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 1.22A 5ekxB-1r6aA:
41.8		 5ekxB-1r6aA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.56A 5ikmA-1r6aA:
41.8		 5ikmA-1r6aA:
69.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.37A 5kqrA-1r6aA:
40.4		 5kqrA-1r6aA:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.28A 5kqsA-1r6aA:
40.2		 5kqsA-1r6aA:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.33A 5m5bA-1r6aA:
40.7		 5m5bA-1r6aA:
60.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.88A 5m5bA-1r6aA:
40.7		 5m5bA-1r6aA:
60.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.45A 5njvA-1r6aA:
40.1		 5njvA-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
 0.89A 5njvA-1r6aA:
40.1		 5njvA-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.38A 5njvB-1r6aA:
40.3		 5njvB-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.87A 5njvB-1r6aA:
40.3		 5njvB-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.65A 5njvC-1r6aA:
39.1		 5njvC-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
LYS A 105
GLU A 111
VAL A 132
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SO4  A 902 (-2.7A)
None
SAH  A 887 (-3.5A)
 1.15A 5njvC-1r6aA:
39.1		 5njvC-1r6aA:
59.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.64A 5njvD-1r6aA:
39.1		 5njvD-1r6aA:
59.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 7 GLU A  35
TYR A 252
ALA A  60
GLY A  58
 SO4  A 905 ( 4.7A)
None
None
SAH  A 887 (-3.0A)
 0.86A 5uxdA-1r6aA:
0.2		 5uxdA-1r6aA:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
LYS A 105
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 181
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.1A)
SAH  A 887 ( 4.2A)
None
 0.37A 5vimA-1r6aA:
40.1		 5vimA-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
PHE A 133
ILE A 147
 SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-4.1A)
SAH  A 887 ( 4.2A)
 1.43A 5vimA-1r6aA:
40.1		 5vimA-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.35A 5vimA-1r6aA:
40.1		 5vimA-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 181
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.1A)
SAH  A 887 ( 4.2A)
None
 0.50A 5vimB-1r6aA:
40.0		 5vimB-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
LYS A 105
HIS A 110
VAL A 132
ILE A 147
LYS A 181
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
None
 0.56A 5vimB-1r6aA:
40.0		 5vimB-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 (-4.5A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.30A 5vimB-1r6aA:
40.0		 5vimB-1r6aA:
61.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.89A 5wz1A-1r6aA:
40.0		 5wz1A-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.87A 5wz1B-1r6aA:
39.9		 5wz1B-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.80A 5wz1C-1r6aA:
39.8		 5wz1C-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
 0.90A 5wz1C-1r6aA:
39.8		 5wz1C-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.87A 5wz1D-1r6aA:
39.9		 5wz1D-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.78A 5wz1E-1r6aA:
39.8		 5wz1E-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
 0.89A 5wz1E-1r6aA:
39.8		 5wz1E-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.86A 5wz1F-1r6aA:
39.9		 5wz1F-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.78A 5wz1G-1r6aA:
39.9		 5wz1G-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
 0.88A 5wz1G-1r6aA:
39.9		 5wz1G-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
None
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.87A 5wz1H-1r6aA:
39.9		 5wz1H-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.55A 5wz2A-1r6aA:
40.0		 5wz2A-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.76A 5wz2A-1r6aA:
40.0		 5wz2A-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
 0.58A 5wz2B-1r6aA:
40.2		 5wz2B-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.75A 5wz2B-1r6aA:
40.2		 5wz2B-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 901 ( 3.9A)
SAH  A 887 (-3.5A)
SAH  A 887 (-3.9A)
SAH  A 887 ( 4.2A)
 0.62A 5wz2C-1r6aA:
39.9		 5wz2C-1r6aA:
58.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1r6a GENOME POLYPROTEIN
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ILE A 147
 SAH  A 887 (-3.0A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.6A)
SAH  A 887 (-3.3A)
SAH  A 887 (-3.5A)
SAH  A 887 (-4.5A)
SO4  A 902 (-2.7A)
SAH  A 887 (-3.5A)
SAH  A 887 ( 4.2A)
 0.85A 5wz2C-1r6aA:
39.9		 5wz2C-1r6aA:
58.70