SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		5 / 8 PHE A 213
ILE A 114
THR A 110
PRO A 211
LEU A 212
 None
 1.43A 1hmyA-1r6eA:
undetectable		 1hmyA-1r6eA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		3 / 3 ILE A 137
LEU A 141
VAL A 161
 None
 0.47A 1mz9B-1r6eA:
undetectable		 1mz9B-1r6eA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		5 / 12 GLU A 146
ALA A 147
GLY A 145
LEU A 115
SER A 116
 None
 1.03A 3g2oA-1r6eA:
undetectable		 3g2oA-1r6eA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		4 / 6 GLU A 143
TYR A 235
LEU A 130
PHE A 140
 None
 1.34A 4twdF-1r6eA:
undetectable
4twdG-1r6eA:
undetectable		 4twdF-1r6eA:
18.63
4twdG-1r6eA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		4 / 7 ASN A 192
VAL A 195
SER A 196
ALA A 199
 None
 0.86A 5fpdA-1r6eA:
undetectable		 5fpdA-1r6eA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		4 / 7 ASN A 192
VAL A 195
SER A 196
ALA A 199
 None
 0.86A 5fpdB-1r6eA:
2.1		 5fpdB-1r6eA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r6e TYPEIII-SECRETED
PROTEIN EFFECTOR:
INVASION-ASSOCIATED
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 147
GLN A 225
THR A 227
 None
 0.71A 5n0oA-1r6eA:
undetectable		 5n0oA-1r6eA:
17.77