SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 ALA A  75
VAL A  68
TRP A  80
None
0.83A 1c4dC-1r6xA:
undetectable
1c4dD-1r6xA:
undetectable
1c4dC-1r6xA:
9.09
1c4dD-1r6xA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 TRP A  80
ALA A  75
VAL A  68
None
0.88A 1c4dC-1r6xA:
undetectable
1c4dD-1r6xA:
undetectable
1c4dC-1r6xA:
9.09
1c4dD-1r6xA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 ALA A 149
VAL A  88
TRP A  35
None
0.89A 1kqeA-1r6xA:
undetectable
1kqeE-1r6xA:
undetectable
1kqeA-1r6xA:
4.81
1kqeE-1r6xA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 ASP A  44
THR A  85
GLU A 128
None
0.62A 1pj7A-1r6xA:
2.3
1pj7A-1r6xA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 ALA A  75
VAL A  68
TRP A  80
None
0.90A 1tkqB-1r6xA:
undetectable
1tkqB-1r6xA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.84A 1v54A-1r6xA:
0.0
1v54J-1r6xA:
0.0
1v54A-1r6xA:
21.48
1v54J-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.93A 1v54N-1r6xA:
0.0
1v54W-1r6xA:
undetectable
1v54N-1r6xA:
21.48
1v54W-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.97A 1v55A-1r6xA:
0.0
1v55J-1r6xA:
undetectable
1v55A-1r6xA:
21.48
1v55J-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.95A 1v55N-1r6xA:
undetectable
1v55W-1r6xA:
undetectable
1v55N-1r6xA:
21.48
1v55W-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 ASP A 151
ILE A 142
VAL A  69
None
0.69A 2avvD-1r6xA:
undetectable
2avvD-1r6xA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.85A 2dyrA-1r6xA:
0.0
2dyrJ-1r6xA:
0.0
2dyrA-1r6xA:
21.48
2dyrJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.91A 2dyrN-1r6xA:
0.0
2dyrW-1r6xA:
undetectable
2dyrN-1r6xA:
21.48
2dyrW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.89A 2dysA-1r6xA:
0.0
2dysJ-1r6xA:
0.0
2dysA-1r6xA:
21.48
2dysJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.86A 2dysN-1r6xA:
0.0
2dysW-1r6xA:
0.0
2dysN-1r6xA:
21.48
2dysW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.85A 2eijA-1r6xA:
0.0
2eijJ-1r6xA:
0.0
2eijA-1r6xA:
21.48
2eijJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.87A 2eijN-1r6xA:
0.0
2eijW-1r6xA:
undetectable
2eijN-1r6xA:
21.48
2eijW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.81A 2eikA-1r6xA:
0.0
2eikJ-1r6xA:
0.0
2eikA-1r6xA:
21.48
2eikJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.88A 2eikN-1r6xA:
0.0
2eikW-1r6xA:
0.0
2eikN-1r6xA:
21.48
2eikW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.83A 2eilA-1r6xA:
0.0
2eilJ-1r6xA:
0.0
2eilA-1r6xA:
21.48
2eilJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.85A 2eilN-1r6xA:
0.0
2eilW-1r6xA:
0.0
2eilN-1r6xA:
21.48
2eilW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.96A 2einA-1r6xA:
undetectable
2einJ-1r6xA:
undetectable
2einA-1r6xA:
21.48
2einJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 GLY A 358
LEU A 365
PHE A 375
HIS A 201
PRO A 199
None
1.03A 2y7kD-1r6xA:
undetectable
2y7kD-1r6xA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.89A 2zxwA-1r6xA:
0.0
2zxwJ-1r6xA:
0.0
2zxwA-1r6xA:
21.48
2zxwJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 SER A  54
LEU A  56
THR A  57
ASP A  64
ILE A 276
None
1.05A 3a35B-1r6xA:
2.0
3a35B-1r6xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.98A 3abkA-1r6xA:
undetectable
3abkJ-1r6xA:
undetectable
3abkA-1r6xA:
21.48
3abkJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
ARG A  40
THR A  38
LEU A  37
None
0.97A 3ablA-1r6xA:
0.0
3ablJ-1r6xA:
undetectable
3ablA-1r6xA:
21.48
3ablJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.84A 3ablA-1r6xA:
0.0
3ablJ-1r6xA:
undetectable
3ablA-1r6xA:
21.48
3ablJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.74A 3ablN-1r6xA:
0.0
3ablW-1r6xA:
undetectable
3ablN-1r6xA:
21.48
3ablW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.79A 3abmA-1r6xA:
0.0
3abmJ-1r6xA:
0.0
3abmA-1r6xA:
21.48
3abmJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.99A 3abmN-1r6xA:
undetectable
3abmW-1r6xA:
undetectable
3abmN-1r6xA:
21.48
3abmW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
None
0.85A 3ag1N-1r6xA:
0.0
3ag1W-1r6xA:
undetectable
3ag1N-1r6xA:
21.48
3ag1W-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.94A 3ag3A-1r6xA:
0.0
3ag3J-1r6xA:
undetectable
3ag3A-1r6xA:
21.48
3ag3J-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
None
0.95A 3ag4N-1r6xA:
0.0
3ag4W-1r6xA:
undetectable
3ag4N-1r6xA:
21.48
3ag4W-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.85A 3asnA-1r6xA:
0.0
3asnJ-1r6xA:
0.0
3asnA-1r6xA:
21.48
3asnJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.77A 3asnN-1r6xA:
0.0
3asnW-1r6xA:
undetectable
3asnN-1r6xA:
21.48
3asnW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.90A 3asnN-1r6xA:
0.0
3asnW-1r6xA:
undetectable
3asnN-1r6xA:
21.48
3asnW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.84A 3asoA-1r6xA:
0.0
3asoJ-1r6xA:
undetectable
3asoA-1r6xA:
21.48
3asoJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.95A 3asoN-1r6xA:
undetectable
3asoW-1r6xA:
undetectable
3asoN-1r6xA:
21.48
3asoW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 SER A 357
GLY A 358
THR A 359
None
0.18A 3k9wA-1r6xA:
9.0
3k9wA-1r6xA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 GLU A 128
LEU A 145
LEU A 227
None
0.77A 3ohtA-1r6xA:
undetectable
3ohtA-1r6xA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 GLU A 128
LEU A 145
LEU A 227
None
0.75A 3ohtB-1r6xA:
undetectable
3ohtB-1r6xA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 GLY A 267
SER A 266
ILE A  82
SER A  72
None
0.84A 3pwwA-1r6xA:
undetectable
3pwwA-1r6xA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A  48
LEU A  49
ARG A  40
THR A  38
None
1.18A 3wg7A-1r6xA:
0.0
3wg7J-1r6xA:
undetectable
3wg7A-1r6xA:
21.48
3wg7J-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 HIS A 222
HIS A 274
ARG A 264
LEU A  47
LEU A  56
None
1.44A 4ac0A-1r6xA:
0.0
4ac0A-1r6xA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 TYR A 144
PHE A  53
LEU A 321
LEU A 261
HIS A 274
None
1.34A 4j03A-1r6xA:
3.9
4j03A-1r6xA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 GLU A 379
TYR A 377
GLU A 373
ARG A 248
None
1.17A 4mi4B-1r6xA:
undetectable
4mi4C-1r6xA:
undetectable
4mi4B-1r6xA:
18.43
4mi4C-1r6xA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
1.11A 5b1aA-1r6xA:
undetectable
5b1aJ-1r6xA:
undetectable
5b1aA-1r6xA:
21.48
5b1aJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.75A 5b1bA-1r6xA:
0.0
5b1bJ-1r6xA:
0.0
5b1bA-1r6xA:
21.48
5b1bJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
1.15A 5b3sA-1r6xA:
undetectable
5b3sJ-1r6xA:
undetectable
5b3sA-1r6xA:
21.48
5b3sJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.92A 5iy5A-1r6xA:
0.0
5iy5J-1r6xA:
0.0
5iy5A-1r6xA:
21.48
5iy5J-1r6xA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
ARG A  40
THR A  38
LEU A  37
None
0.93A 5iy5N-1r6xA:
0.0
5iy5W-1r6xA:
undetectable
5iy5N-1r6xA:
21.48
5iy5W-1r6xA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
3 / 3 HIS A 236
ASP A 234
HIS A 235
CO  A3000 (-3.2A)
None
CO  A3000 (-3.4A)
0.93A 5n1tW-1r6xA:
undetectable
5n1tW-1r6xA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 ILE A  48
ASP A  11
LEU A  74
GLY A 282
TYR A 281
None
1.13A 5uxdB-1r6xA:
undetectable
5uxdB-1r6xA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A 233
ILE A 246
HIS A 204
PHE A 255
None
0.81A 5vkqB-1r6xA:
undetectable
5vkqC-1r6xA:
undetectable
5vkqB-1r6xA:
13.24
5vkqC-1r6xA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A 233
ILE A 246
HIS A 204
PHE A 255
None
0.85A 5vkqC-1r6xA:
undetectable
5vkqD-1r6xA:
undetectable
5vkqC-1r6xA:
13.24
5vkqD-1r6xA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.71A 5x1fA-1r6xA:
0.0
5x1fJ-1r6xA:
undetectable
5x1fA-1r6xA:
21.48
5x1fJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.73A 5xdqA-1r6xA:
0.0
5xdqJ-1r6xA:
undetectable
5xdqA-1r6xA:
21.48
5xdqJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.91A 5xdqN-1r6xA:
0.0
5xdqW-1r6xA:
undetectable
5xdqN-1r6xA:
21.48
5xdqW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.81A 5xdxA-1r6xA:
0.0
5xdxJ-1r6xA:
undetectable
5xdxA-1r6xA:
21.48
5xdxJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 12 LEU A 321
ILE A 276
LEU A  60
VAL A  68
LEU A  12
None
1.03A 5ycnA-1r6xA:
undetectable
5ycnA-1r6xA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
None
0.98A 5z86N-1r6xA:
0.0
5z86W-1r6xA:
0.0
5z86N-1r6xA:
21.48
5z86W-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.78A 5zcoA-1r6xA:
0.0
5zcoJ-1r6xA:
undetectable
5zcoA-1r6xA:
21.48
5zcoJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
None
0.98A 5zcoN-1r6xA:
0.0
5zcoW-1r6xA:
undetectable
5zcoN-1r6xA:
21.48
5zcoW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
1.10A 5zcpA-1r6xA:
undetectable
5zcpJ-1r6xA:
undetectable
5zcpA-1r6xA:
21.48
5zcpJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.92A 5zcpN-1r6xA:
undetectable
5zcpW-1r6xA:
undetectable
5zcpN-1r6xA:
21.48
5zcpW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.74A 5zcqA-1r6xA:
undetectable
5zcqJ-1r6xA:
undetectable
5zcqA-1r6xA:
21.48
5zcqJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
None
0.76A 5zcqN-1r6xA:
0.0
5zcqW-1r6xA:
0.0
5zcqN-1r6xA:
21.48
5zcqW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 8 VAL A 209
TYR A 249
HIS A 204
TYR A 377
None
0.99A 6gneB-1r6xA:
undetectable
6gneB-1r6xA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
4 / 6 ILE A  48
LEU A  49
ARG A  40
THR A  38
None
1.01A 6nmfN-1r6xA:
undetectable
6nmfW-1r6xA:
undetectable
6nmfN-1r6xA:
21.48
6nmfW-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.85A 6nmpA-1r6xA:
0.0
6nmpJ-1r6xA:
undetectable
6nmpA-1r6xA:
21.48
6nmpJ-1r6xA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae)
5 / 5 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
None
0.96A 6nmpN-1r6xA:
0.0
6nmpW-1r6xA:
0.0
6nmpN-1r6xA:
21.48
6nmpW-1r6xA:
11.44