SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		4 / 7 ARG A 163
GLY A 162
ILE A 174
GLU A 164
 None
 1.04A 4g0vA-1r71A:
undetectable		 4g0vA-1r71A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		5 / 12 ALA A 158
ILE A 161
ASN A 150
LEU A 147
GLY A 179
 None
 1.12A 4r38A-1r71A:
undetectable		 4r38A-1r71A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		5 / 12 ALA A 158
ILE A 161
ASN A 150
LEU A 147
GLY A 179
 None
 1.09A 4r38B-1r71A:
undetectable		 4r38B-1r71A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		5 / 12 ALA A 158
ILE A 161
ASN A 150
LEU A 147
GLY A 179
 None
 1.10A 4r38C-1r71A:
undetectable		 4r38C-1r71A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		5 / 12 ALA A 158
ILE A 161
ASN A 150
LEU A 147
GLY A 179
 None
 1.09A 4r38D-1r71A:
undetectable		 4r38D-1r71A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		5 / 12 ALA A 175
ALA A 158
ILE A 161
ASN A 150
GLN A 148
 None
 1.08A 4r3aA-1r71A:
undetectable		 4r3aA-1r71A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		3 / 3 VAL A 217
PHE A 202
ARG A 155
 None
 0.81A 4xr4B-1r71A:
undetectable		 4xr4B-1r71A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		4 / 4 GLU A 156
PRO A 154
ILE A 157
LEU A 152
 None
 1.22A 5m45A-1r71A:
0.6		 5m45A-1r71A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1r71 TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB
(Escherichia
coli) 		4 / 4 GLU A 156
PRO A 154
ILE A 157
LEU A 152
 None
 1.24A 5m45J-1r71A:
0.0		 5m45J-1r71A:
15.49