SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 1r77 CELL WALL TARGETING
DOMAIN OF
GLYCYLGLYCINE
ENDOPEPTIDASE ALE-1
(Staphylococcus
capitis) 		3 / 3 ARG A 345
GLU A 283
TYR A 271
 None
 0.87A 3k37B-1r77A:
undetectable		 3k37B-1r77A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1r77 CELL WALL TARGETING
DOMAIN OF
GLYCYLGLYCINE
ENDOPEPTIDASE ALE-1
(Staphylococcus
capitis) 		3 / 3 HIS A 327
SER A 350
GLU A 349
 None
 0.89A 3s8pA-1r77A:
undetectable		 3s8pA-1r77A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1r77 CELL WALL TARGETING
DOMAIN OF
GLYCYLGLYCINE
ENDOPEPTIDASE ALE-1
(Staphylococcus
capitis) 		3 / 3 GLU A 320
TRP A 329
ASN A 274
 None
 1.15A 5dv4A-1r77A:
undetectable		 5dv4A-1r77A:
14.11