SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
5 / 10 VAL A 277
LEU A 324
LEU A 306
GLY A 267
ALA A 268
None
AOG  A 452 ( 4.2A)
HG  A 402 ( 4.2A)
None
None
1.25A 2xf3A-1r82A:
undetectable
2xf3A-1r82A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
4 / 5 LEU A 118
GLY A 117
MET A 142
PHE A 269
None
1.17A 3uq6B-1r82A:
undetectable
3uq6B-1r82A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
4 / 4 LEU A 118
GLY A 117
MET A 142
PHE A 269
None
1.12A 3vaqB-1r82A:
undetectable
3vaqB-1r82A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
4 / 6 GLY A 230
LEU A 310
ASN A 307
GLU A 303
None
None
None
AOG  A 452 (-2.6A)
1.00A 3zqtA-1r82A:
undetectable
3zqtA-1r82A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
4 / 7 PHE A 229
VAL A  95
GLY A 221
PHE A 269
None
0.92A 4ejjB-1r82A:
undetectable
4ejjB-1r82A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
5 / 12 ILE A 224
LEU A 324
VAL A 210
LEU A 225
PHE A 229
None
AOG  A 452 ( 4.2A)
None
None
None
1.08A 5bykA-1r82A:
0.0
5bykA-1r82A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
3 / 3 ASP A 262
VAL A 318
LEU A 232
None
0.59A 5e5jB-1r82A:
undetectable
5e5jB-1r82A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1r82 GLYCOPROTEIN-FUCOSYL
GALACTOSIDE
ALPHA-GALACTOSYLTRAN
SFERASE

(Homo
sapiens)
4 / 5 GLY A 167
THR A 166
GLY A 230
LEU A 118
None
0.93A 5jlcA-1r82A:
undetectable
5jlcA-1r82A:
20.00