SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		4 / 6 LEU A  41
ASP A 172
MET A 160
LEU A  48
 None
 1.19A 1errB-1r8iA:
1.7		 1errB-1r8iA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		5 / 12 MET A 131
LEU A 135
ASN A 132
MET A  65
ILE A 128
 None
 1.19A 1p93A-1r8iA:
undetectable		 1p93A-1r8iA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		4 / 5 LEU A  41
ASP A 172
MET A 160
LEU A  48
 None
 1.17A 2jfaA-1r8iA:
undetectable		 2jfaA-1r8iA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		4 / 5 LEU A  41
ASP A 172
MET A 160
LEU A  48
 None
 1.22A 2qxsA-1r8iA:
1.7		 2qxsA-1r8iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		4 / 5 LEU A  41
ASP A 172
MET A 160
LEU A  48
 None
 1.22A 2qxsB-1r8iA:
undetectable		 2qxsB-1r8iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1r8i TRAC
(Escherichia
coli) 		4 / 6 SER A 175
ASP A 178
THR A 164
ILE A 167
 None
 0.97A 4acbC-1r8iA:
undetectable		 4acbC-1r8iA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 1r8i TRAC
(Escherichia
coli) 		5 / 12 MET A 131
LEU A 135
ASN A 132
MET A  65
ILE A 128
 None
 1.27A 4p6xA-1r8iA:
undetectable		 4p6xA-1r8iA:
21.67