SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 1r8n KUNITZ TRYPSIN
INHIBITOR
(Delonix
regia) 		4 / 9 ILE A  22
PHE A  83
VAL A  61
GLU A  19
 None
 0.81A 2vufA-1r8nA:
undetectable		 2vufA-1r8nA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 1r8n KUNITZ TRYPSIN
INHIBITOR
(Delonix
regia) 		3 / 3 TYR A  74
LYS A  72
LYS A   5
 None
 1.31A 5dbyA-1r8nA:
undetectable		 5dbyA-1r8nA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1r8n KUNITZ TRYPSIN
INHIBITOR
(Delonix
regia) 		5 / 12 GLY A  58
ILE A  48
GLU A  19
VAL A  61
ILE A  81
 None
 0.87A 6ectA-1r8nA:
undetectable		 6ectA-1r8nA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1r8n KUNITZ TRYPSIN
INHIBITOR
(Delonix
regia) 		5 / 12 GLY A  58
ILE A  48
GLU A  19
VAL A  61
ILE A  81
 None
 0.85A 6ecxA-1r8nA:
undetectable		 6ecxA-1r8nA:
20.25