SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		4 / 5 PHE A 117
VAL A  54
VAL A  12
ASP A 111
 None
 1.40A 1dz6B-1r9cA:
0.0		 1dz6B-1r9cA:
14.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_A_PPFA5001_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 9 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.87A 1nkiA-1r9cA:
15.9
1nkiB-1r9cA:
15.8		 1nkiA-1r9cA:
34.44
1nkiB-1r9cA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_B_PPFB5002_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 9 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.88A 1nkiA-1r9cA:
15.9
1nkiB-1r9cA:
15.8		 1nkiA-1r9cA:
34.44
1nkiB-1r9cA:
34.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.73A 4ir0A-1r9cA:
15.7
4ir0B-1r9cA:
16.4		 4ir0A-1r9cA:
29.68
4ir0B-1r9cA:
29.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.74A 4ir0A-1r9cA:
15.7
4ir0B-1r9cA:
16.4		 4ir0A-1r9cA:
29.68
4ir0B-1r9cA:
29.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 12 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.71A 4jd1A-1r9cA:
15.8
4jd1B-1r9cA:
15.8		 4jd1A-1r9cA:
29.68
4jd1B-1r9cA:
29.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 12 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.83A 4jd1A-1r9cA:
15.8
4jd1B-1r9cA:
15.8		 4jd1A-1r9cA:
29.68
4jd1B-1r9cA:
29.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 12 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.75A 4jh3A-1r9cA:
16.5
4jh3B-1r9cA:
16.4		 4jh3A-1r9cA:
32.43
4jh3B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.75A 4jh3A-1r9cA:
16.5
4jh3B-1r9cA:
16.4		 4jh3A-1r9cA:
32.43
4jh3B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.75A 4jh4A-1r9cA:
16.4
4jh4B-1r9cA:
16.4		 4jh4A-1r9cA:
32.43
4jh4B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.75A 4jh4A-1r9cA:
16.4
4jh4B-1r9cA:
16.4		 4jh4A-1r9cA:
32.43
4jh4B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.74A 4jh5A-1r9cA:
16.4
4jh5B-1r9cA:
16.5		 4jh5A-1r9cA:
32.43
4jh5B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 11 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.74A 4jh5A-1r9cA:
16.4
4jh5B-1r9cA:
16.5		 4jh5A-1r9cA:
32.43
4jh5B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 10 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.77A 4jh6A-1r9cA:
16.4
4jh6B-1r9cA:
16.4		 4jh6A-1r9cA:
32.43
4jh6B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 10 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.73A 4jh6A-1r9cA:
16.4
4jh6B-1r9cA:
16.4		 4jh6A-1r9cA:
32.43
4jh6B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 10 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.76A 4jh8A-1r9cA:
16.3
4jh8B-1r9cA:
16.3		 4jh8A-1r9cA:
32.43
4jh8B-1r9cA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 10 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.76A 4jh8A-1r9cA:
16.3
4jh8B-1r9cA:
16.3		 4jh8A-1r9cA:
32.43
4jh8B-1r9cA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		4 / 6 LEU A 119
LEU A  91
VAL A  86
PHE A 117
 None
 1.09A 4uswA-1r9cA:
undetectable		 4uswA-1r9cA:
15.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3D_A_FCNA205_1
(FOSFOMYCIN
RESISTANCE PROTEIN)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 10 TYR A  67
HIS A  69
TYR A 108
GLU A 118
ARG A 127
 None
MN  A2001 (-3.2A)
None
MN  A2001 (-2.5A)
None
 0.87A 5v3dA-1r9cA:
15.4
5v3dB-1r9cA:
15.4		 5v3dA-1r9cA:
33.11
5v3dB-1r9cA:
33.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1r9c GLUTATHIONE
TRANSFERASE
(Mesorhizobium
loti) 		5 / 12 LEU A   5
ILE A  52
TYR A  82
LEU A 119
ILE A  70
 None
 1.16A 5y2tB-1r9cA:
undetectable		 5y2tB-1r9cA:
undetectable