SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 9 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.58A 1bkfA-1r9hA:
19.7		 1bkfA-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TYR A  96
ILE A 105
PHE A 113
 None
 0.59A 1c9hA-1r9hA:
19.6		 1c9hA-1r9hA:
38.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.52A 1fapA-1r9hA:
20.1		 1fapA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 12 TYR A  40
PHE A  60
VAL A  69
TRP A  73
ILE A 105
PHE A 113
 None
 1.15A 1fapA-1r9hA:
20.1		 1fapA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.61A 1fkbA-1r9hA:
20.1		 1fkbA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
TRP A  73
ILE A 105
 None
 1.25A 1fkbA-1r9hA:
20.1		 1fkbA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.59A 1fkfA-1r9hA:
19.8		 1fkfA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.60A 1fkjA-1r9hA:
19.8		 1fkjA-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
ILE A 105
PHE A 113
 None
 0.62A 1fklA-1r9hA:
20.0		 1fklA-1r9hA:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
TRP A  73
ILE A 105
 None
 1.26A 1fklA-1r9hA:
20.0		 1fklA-1r9hA:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 12 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.39A 1fklA-1r9hA:
20.0		 1fklA-1r9hA:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 12 TYR A  40
ASP A  51
GLY A  65
TRP A  73
PHE A 113
 None
 0.88A 1pbkA-1r9hA:
18.7		 1pbkA-1r9hA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 12 TYR A  40
ASP A  51
GLY A  67
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.63A 1pbkA-1r9hA:
18.7		 1pbkA-1r9hA:
40.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 9 TYR A  40
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.57A 1q6iA-1r9hA:
17.1		 1q6iA-1r9hA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
ARG A  56
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.63A 1q6iB-1r9hA:
16.9		 1q6iB-1r9hA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 8 ALA A  86
GLY A  24
GLY A  83
PRO A  30
ALA A  78
 None
 1.23A 1sguA-1r9hA:
undetectable		 1sguA-1r9hA:
22.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.70A 1tcoC-1r9hA:
19.7		 1tcoC-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.61A 1yatA-1r9hA:
21.7		 1yatA-1r9hA:
42.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.55A 2dg3A-1r9hA:
19.9		 2dg3A-1r9hA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		7 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TYR A  96
PHE A 113
 None
 0.62A 2dg4A-1r9hA:
19.4		 2dg4A-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A 105
 None
 1.12A 2dg4A-1r9hA:
19.4		 2dg4A-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
PHE A 113
 None
 0.55A 2dg9A-1r9hA:
19.7		 2dg9A-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A 105
 None
 1.15A 2dg9A-1r9hA:
19.7		 2dg9A-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 11 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TYR A  96
PHE A 113
 None
 0.28A 2dg9A-1r9hA:
19.7		 2dg9A-1r9hA:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.58A 2fkeA-1r9hA:
20.0		 2fkeA-1r9hA:
44.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		7 / 11 TYR A  40
PHE A  50
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
 None
 0.93A 2vcdA-1r9hA:
14.7		 2vcdA-1r9hA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 11 TYR A  40
PHE A  50
PHE A  60
TRP A  73
TYR A  96
 None
 1.37A 2vcdA-1r9hA:
14.7		 2vcdA-1r9hA:
28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
PHE A  50
ASP A  51
ARG A  56
PHE A  60
VAL A  69
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.77A 2vn1A-1r9hA:
22.0		 2vn1A-1r9hA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 10 TYR A  40
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.51A 2vn1B-1r9hA:
22.0		 2vn1B-1r9hA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.74A 2vn1B-1r9hA:
22.0		 2vn1B-1r9hA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.57A 3ihzA-1r9hA:
22.1		 3ihzA-1r9hA:
47.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 8 TYR A  40
ASP A  51
PHE A  60
TRP A  73
TYR A  96
ILE A 105
 None
 0.34A 3ihzB-1r9hA:
22.9		 3ihzB-1r9hA:
47.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 10 TYR A  40
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.60A 3kz7A-1r9hA:
19.1		 3kz7A-1r9hA:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.64A 3o5rA-1r9hA:
22.7		 3o5rA-1r9hA:
49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.63A 3uf8A-1r9hA:
20.2		 3uf8A-1r9hA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.47A 3uqaA-1r9hA:
20.1		 3uqaA-1r9hA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.65A 3uqaA-1r9hA:
20.1		 3uqaA-1r9hA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 8 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.39A 3uqbA-1r9hA:
19.8		 3uqbA-1r9hA:
31.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.61A 3vawA-1r9hA:
19.5		 3vawA-1r9hA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.61A 4drhA-1r9hA:
21.5		 4drhA-1r9hA:
46.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 12 ASP A  51
TYR A  96
PRO A 103
ILE A 105
PHE A 113
 None
 1.24A 4drhD-1r9hA:
21.5		 4drhD-1r9hA:
46.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.56A 4drhD-1r9hA:
21.5		 4drhD-1r9hA:
46.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
ARG A  56
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.81A 4driA-1r9hA:
23.6		 4driA-1r9hA:
46.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.53A 4driA-1r9hA:
23.6		 4driA-1r9hA:
46.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.57A 4drjA-1r9hA:
23.2		 4drjA-1r9hA:
53.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		4 / 8 SER A  53
ILE A  90
VAL A  16
PHE A  88
 None
 0.87A 4dx7B-1r9hA:
undetectable		 4dx7B-1r9hA:
8.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.69A 4dz2A-1r9hA:
20.0
4dz2B-1r9hA:
20.2		 4dz2A-1r9hA:
45.60
4dz2B-1r9hA:
45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.66A 4dz2A-1r9hA:
20.0
4dz2B-1r9hA:
20.2		 4dz2A-1r9hA:
45.60
4dz2B-1r9hA:
45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.64A 4dz3A-1r9hA:
20.1		 4dz3A-1r9hA:
45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.63A 4dz3B-1r9hA:
15.1		 4dz3B-1r9hA:
45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.61A 4laxA-1r9hA:
23.6		 4laxA-1r9hA:
41.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 10 VAL A  16
SER A  92
GLY A  95
ASP A   7
THR A   9
 None
 1.27A 4mm7A-1r9hA:
undetectable		 4mm7A-1r9hA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 12 VAL A  16
SER A  92
GLY A  95
ASP A   7
THR A   9
 None
 1.21A 4mm8A-1r9hA:
undetectable		 4mm8A-1r9hA:
14.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.65A 4nnrA-1r9hA:
16.1
4nnrB-1r9hA:
16.2		 4nnrA-1r9hA:
42.00
4nnrB-1r9hA:
42.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 10 TYR A  40
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.67A 4nnrB-1r9hA:
16.2		 4nnrB-1r9hA:
42.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 10 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.47A 4nnrB-1r9hA:
16.2		 4nnrB-1r9hA:
42.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 10 TYR A  40
ASP A  51
ILE A  70
TYR A  96
PHE A 113
 None
 0.74A 4odoA-1r9hA:
11.6		 4odoA-1r9hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 10 TYR A  40
ASP A  51
ILE A  70
TYR A  96
PHE A 113
 None
 0.70A 4odoB-1r9hA:
11.4		 4odoB-1r9hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 10 TYR A  40
ASP A  51
ILE A  70
TYR A  96
PHE A 113
 None
 0.71A 4odoC-1r9hA:
11.3		 4odoC-1r9hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 12 TYR A  40
ASP A  51
ILE A  70
TYR A  96
ILE A 105
PHE A 113
 None
 0.73A 4odrA-1r9hA:
13.1
4odrB-1r9hA:
13.1		 4odrA-1r9hA:
23.78
4odrB-1r9hA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		5 / 11 TYR A  40
ASP A  51
ILE A  70
TYR A  96
PHE A 113
 None
 0.71A 4odrA-1r9hA:
13.1
4odrB-1r9hA:
13.1		 4odrA-1r9hA:
23.78
4odrB-1r9hA:
23.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.61A 4qt2A-1r9hA:
22.6		 4qt2A-1r9hA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.54A 4qt3A-1r9hA:
20.9		 4qt3A-1r9hA:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 12 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.72A 5b8iC-1r9hA:
18.6		 5b8iC-1r9hA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 11 TYR A  40
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.50A 5d75A-1r9hA:
19.3		 5d75A-1r9hA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 11 TYR A  40
ASP A  51
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.56A 5gpgA-1r9hA:
19.8		 5gpgA-1r9hA:
39.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 12 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TYR A  96
ILE A 105
PHE A 113
 None
 0.65A 5hkgA-1r9hA:
19.7		 5hkgA-1r9hA:
38.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.60A 5huaA-1r9hA:
21.9		 5huaA-1r9hA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
 None
 0.72A 5hw8A-1r9hA:
18.1
5hw8D-1r9hA:
18.2		 5hw8A-1r9hA:
34.93
5hw8D-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.66A 5hw8B-1r9hA:
18.1		 5hw8B-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 10 TYR A  40
ASP A  51
ARG A  56
VAL A  69
ILE A  70
TRP A  73
TYR A  96
LEU A 111
PHE A 113
 None
 0.65A 5hw8C-1r9hA:
18.0
5hw8H-1r9hA:
15.0		 5hw8C-1r9hA:
34.93
5hw8H-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.69A 5hw8D-1r9hA:
18.2		 5hw8D-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		8 / 11 TYR A  40
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.51A 5hw8E-1r9hA:
18.0		 5hw8E-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		7 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
TRP A  73
TYR A  96
PHE A 113
 None
 0.75A 5hw8E-1r9hA:
18.0		 5hw8E-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		7 / 12 TYR A  40
ASP A  51
PHE A  60
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.68A 5hw8B-1r9hA:
18.1
5hw8F-1r9hA:
14.6
5hw8G-1r9hA:
17.7		 5hw8B-1r9hA:
34.93
5hw8F-1r9hA:
34.93
5hw8G-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		7 / 12 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
PHE A 113
 None
 0.35A 5hw8B-1r9hA:
18.1
5hw8F-1r9hA:
14.6
5hw8G-1r9hA:
17.7		 5hw8B-1r9hA:
34.93
5hw8F-1r9hA:
34.93
5hw8G-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		9 / 11 TYR A  40
ASP A  51
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.69A 5hw8G-1r9hA:
17.7		 5hw8G-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 8 TYR A  40
ASP A  51
PHE A  60
ILE A  70
TRP A  73
PHE A 113
 None
 0.72A 5hw8H-1r9hA:
15.0		 5hw8H-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		6 / 8 TYR A  40
PHE A  60
VAL A  69
ILE A  70
TRP A  73
PHE A 113
 None
 0.64A 5hw8H-1r9hA:
15.0		 5hw8H-1r9hA:
34.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 11 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.63A 5hwcA-1r9hA:
19.9		 5hwcA-1r9hA:
46.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 12 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.62A 6mkeA-1r9hA:
21.9
6mkeD-1r9hA:
22.1		 6mkeA-1r9hA:
43.90
6mkeD-1r9hA:
43.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 12 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.55A 6mkeB-1r9hA:
21.9
6mkeC-1r9hA:
21.9		 6mkeB-1r9hA:
43.90
6mkeC-1r9hA:
43.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.57A 6mkeC-1r9hA:
21.9		 6mkeC-1r9hA:
43.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1r9h FK506 BINDING
PROTEIN FAMILY
(Caenorhabditis
elegans) 		10 / 10 TYR A  40
ASP A  51
ARG A  56
PHE A  60
VAL A  69
ILE A  70
TRP A  73
TYR A  96
ILE A 105
PHE A 113
 None
 0.56A 6mkeD-1r9hA:
22.1		 6mkeD-1r9hA:
43.90