SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1r9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1r9w REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		4 / 5 GLU A 338
GLN A 272
HIS A 270
GLY A 332
 None
 1.32A 3pp1A-1r9wA:
undetectable		 3pp1A-1r9wA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1r9w REPLICATION PROTEIN
E1
(Alphapapillomavi
rus
7) 		6 / 12 ILE A 282
LEU A 304
PHE A 258
ILE A 266
LEU A 286
ILE A 271
 None
 1.49A 4i13A-1r9wA:
undetectable		 4i13A-1r9wA:
22.22