SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1raj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 5 LEU A 253
VAL A 252
LEU A  85
GLN A  84
 None
 0.90A 1fbmE-1rajA:
undetectable		 1fbmE-1rajA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 ASN A 301
ASN A 302
ILE A 324
GLY A 207
 None
 0.96A 1oniA-1rajA:
undetectable
1oniB-1rajA:
undetectable		 1oniA-1rajA:
20.62
1oniB-1rajA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 ASN A 301
ASN A 302
ILE A 324
GLY A 207
 None
 0.96A 1oniD-1rajA:
undetectable
1oniF-1rajA:
undetectable		 1oniD-1rajA:
20.62
1oniF-1rajA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.08A 1p7lC-1rajA:
undetectable		 1p7lC-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.08A 1p7lD-1rajA:
undetectable		 1p7lD-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.09A 1rg9A-1rajA:
undetectable		 1rg9A-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.09A 1rg9B-1rajA:
undetectable		 1rg9B-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.07A 1rg9C-1rajA:
undetectable		 1rg9C-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.07A 1rg9D-1rajA:
undetectable		 1rg9D-1rajA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		3 / 3 THR A 372
ASP A 328
SER A 294
 None
 0.78A 2nxeA-1rajA:
undetectable		 2nxeA-1rajA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		3 / 3 THR A 372
ASP A 328
SER A 294
 None
 0.84A 2nxeB-1rajA:
undetectable		 2nxeB-1rajA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.18A 2obvA-1rajA:
undetectable		 2obvA-1rajA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 ASN A 301
SER A 298
ALA A 325
ASP A 329
 None
 1.32A 3aruA-1rajA:
undetectable		 3aruA-1rajA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		5 / 12 PHE A 230
SER A 333
THR A 312
LEU A 321
THR A 365
 None
 1.19A 3hj3C-1rajA:
undetectable		 3hj3C-1rajA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		3 / 3 PRO A 214
PHE A 373
ALA A 209
 None
 0.72A 3itaD-1rajA:
0.0		 3itaD-1rajA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.17A 3kvvA-1rajA:
undetectable		 3kvvA-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.15A 3kvvB-1rajA:
undetectable		 3kvvB-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.11A 3kvvC-1rajA:
undetectable		 3kvvC-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.13A 3kvvD-1rajA:
undetectable		 3kvvD-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.14A 3kvvE-1rajA:
undetectable		 3kvvE-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 6 LEU A 374
PHE A 373
ILE A 324
ALA A 325
 None
 0.74A 3mdrA-1rajA:
0.2		 3mdrA-1rajA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		6 / 9 ASP A 238
ASN A 297
TYR A 326
GLY A 327
ASP A 328
ASP A 329
 None
 0.66A 3sfuA-1rajA:
14.4		 3sfuA-1rajA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		6 / 9 ASP A 238
THR A 293
TYR A 326
GLY A 327
ASP A 328
ASP A 329
 None
 0.54A 3sfuA-1rajA:
14.4		 3sfuA-1rajA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		7 / 9 ASP A 238
ASN A 297
TYR A 326
GLY A 327
ASP A 328
ASP A 329
LEU A 374
 None
 0.66A 3sfuB-1rajA:
19.6		 3sfuB-1rajA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		5 / 11 ASP A 238
THR A 293
ASN A 297
GLY A 327
ASP A 328
 None
 0.69A 3sfuC-1rajA:
6.2		 3sfuC-1rajA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.21A 4kttA-1rajA:
undetectable		 4kttA-1rajA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.20A 4kttC-1rajA:
undetectable		 4kttC-1rajA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.18A 4odjA-1rajA:
undetectable		 4odjA-1rajA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 5a1iA-1rajA:
undetectable		 5a1iA-1rajA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 5a1iA-1rajA:
undetectable		 5a1iA-1rajA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
GLY A 425
VAL A 391
HIS A 389
 None
 0.74A 5f8yA-1rajA:
0.0		 5f8yA-1rajA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
GLY A 425
VAL A 391
HIS A 389
 None
 0.74A 5f8yB-1rajA:
0.0		 5f8yB-1rajA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 5 CYH A 418
ILE A 397
LEU A 433
HIS A 398
 None
 1.39A 5hrqC-1rajA:
undetectable
5hrqD-1rajA:
undetectable
5hrqL-1rajA:
undetectable		 5hrqC-1rajA:
6.88
5hrqD-1rajA:
9.48
5hrqL-1rajA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.14A 5t8sB-1rajA:
undetectable		 5t8sB-1rajA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.15A 6fboA-1rajA:
undetectable		 6fboA-1rajA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.19A 6fcbA-1rajA:
undetectable		 6fcbA-1rajA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 6fcdA-1rajA:
undetectable		 6fcdA-1rajA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1raj GENOME POLYPROTEIN
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.14A 6g6rA-1rajA:
undetectable		 6g6rA-1rajA:
23.78