SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  69
TRP A  70
 None
 0.78A 1av2A-1rblA:
undetectable
1av2B-1rblA:
undetectable		 1av2A-1rblA:
4.08
1av2B-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.76A 1av2C-1rblA:
undetectable
1av2D-1rblA:
undetectable		 1av2C-1rblA:
4.08
1av2D-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.65A 1bdwA-1rblA:
undetectable
1bdwB-1rblA:
undetectable		 1bdwA-1rblA:
4.08
1bdwB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus) 		4 / 6 LEU A 390
LEU A 170
HIS A 383
LEU M  18
 None
 0.91A 1errA-1rblA:
undetectable		 1errA-1rblA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 GLY A 337
LEU A 343
VAL A 346
ALA A 378
PHE A 394
 None
 1.21A 1gseA-1rblA:
undetectable		 1gseA-1rblA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 6 PHE A 311
ILE A 309
LYS A 316
ALA A 315
 None
 1.15A 1hk2A-1rblA:
undetectable		 1hk2A-1rblA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1jnoA-1rblA:
undetectable		 1jnoA-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1jnoB-1rblA:
undetectable		 1jnoB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.92A 1jo3A-1rblA:
undetectable		 1jo3A-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.91A 1jo3B-1rblA:
undetectable		 1jo3B-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1jo4A-1rblA:
undetectable		 1jo4A-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1jo4B-1rblA:
undetectable		 1jo4B-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ARG A 431
GLY A 166
ASP A 396
 None
 0.50A 1kf6A-1rblA:
undetectable
1kf6B-1rblA:
undetectable		 1kf6A-1rblA:
22.37
1kf6B-1rblA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 7 LEU A 400
MET A 266
TYR A 239
LEU A 197
 None
 1.07A 1kt3A-1rblA:
0.0		 1kt3A-1rblA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 11 PRO A 263
LEU A 240
VAL A 189
GLY A 186
LEU A 260
 None
 1.50A 1lwcA-1rblA:
0.0		 1lwcA-1rblA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.92A 1magA-1rblA:
undetectable		 1magA-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.92A 1magB-1rblA:
undetectable		 1magB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.92A 1ng8A-1rblA:
undetectable		 1ng8A-1rblA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.92A 1ng8B-1rblA:
undetectable		 1ng8B-1rblA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.84A 1nrmA-1rblA:
undetectable		 1nrmA-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.84A 1nrmB-1rblA:
undetectable		 1nrmB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1nruA-1rblA:
undetectable		 1nruA-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.93A 1nruB-1rblA:
undetectable		 1nruB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 LEU A 375
HIS A 153
ILE A 264
PHE A 199
TYR A 165
 None
 1.35A 1ot7B-1rblA:
0.0		 1ot7B-1rblA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 11 SER A  61
PHE A  40
LEU A 135
VAL A 313
VAL A 121
 None
 1.37A 1q23I-1rblA:
undetectable		 1q23I-1rblA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  69
TRP A  70
 None
 0.78A 1w5uA-1rblA:
undetectable
1w5uB-1rblA:
undetectable		 1w5uA-1rblA:
4.08
1w5uB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.90A 1w5uA-1rblA:
undetectable
1w5uB-1rblA:
undetectable		 1w5uA-1rblA:
4.08
1w5uB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.80A 1w5uC-1rblA:
undetectable
1w5uD-1rblA:
undetectable		 1w5uC-1rblA:
4.08
1w5uD-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus;
Synechococcus
elongatus) 		4 / 8 ASP A 396
GLY M 103
PHE M 104
TYR A 165
 None
 1.05A 2aouA-1rblA:
undetectable		 2aouA-1rblA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 ARG A 187
GLY A 186
THR A 200
ILE A 174
 None
 0.83A 2f9wA-1rblA:
undetectable
2f9wB-1rblA:
undetectable		 2f9wA-1rblA:
20.26
2f9wB-1rblA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  66
ALA A  15
VAL A  17
 None
 0.71A 2izqA-1rblA:
undetectable
2izqB-1rblA:
undetectable		 2izqA-1rblA:
4.08
2izqB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.69A 2izqC-1rblA:
undetectable
2izqD-1rblA:
undetectable		 2izqC-1rblA:
4.08
2izqD-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus;
Synechococcus
elongatus) 		3 / 3 LEU M  18
PRO M  19
ARG A 435
 None
 0.58A 2qd5A-1rblM:
undetectable		 2qd5A-1rblM:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 7 THR A 342
GLY A 337
LEU A 390
PHE A 394
 None
 0.95A 2vl2B-1rblA:
undetectable		 2vl2B-1rblA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 LEU A 291
THR A 243
VAL A 242
ALA A 276
 None
 0.95A 3ax9A-1rblA:
undetectable		 3ax9A-1rblA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 PHE A 394
GLY A 171
ASP A 396
ILE A 393
PRO A 376
 None
 1.25A 3eeoA-1rblA:
undetectable		 3eeoA-1rblA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 ALA A 458
GLY A 416
ASN A 420
HIS A 383
VAL A 384
 None
 1.01A 3f8wA-1rblA:
undetectable		 3f8wA-1rblA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 GLY A 416
GLY A 408
ASN A 420
HIS A 383
VAL A 384
 None
 1.20A 3f8wA-1rblA:
undetectable		 3f8wA-1rblA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 4 ARG A 431
ASP A 397
ASP A 396
PRO A 168
 None
 1.42A 3fgrB-1rblA:
0.0		 3fgrB-1rblA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 GLU A 447
GLY A 449
VAL A 391
GLY A 441
ILE A 444
 None
 1.29A 3k13A-1rblA:
8.3		 3k13A-1rblA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ALA A  15
VAL A  17
TRP A  66
 None
 0.72A 3l8lA-1rblA:
undetectable
3l8lB-1rblA:
undetectable		 3l8lA-1rblA:
4.08
3l8lB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.75A 3l8lA-1rblA:
undetectable
3l8lB-1rblA:
undetectable		 3l8lA-1rblA:
4.08
3l8lB-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 TRP A  70
ALA A  15
VAL A  69
 None
 0.71A 3l8lC-1rblA:
undetectable
3l8lD-1rblA:
undetectable		 3l8lC-1rblA:
4.08
3l8lD-1rblA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 9 ILE A 309
LEU A 314
ILE A 116
PHE A 274
GLY A 273
 None
 1.09A 3sj4X-1rblA:
undetectable		 3sj4X-1rblA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 LEU A 291
THR A 243
VAL A 242
ALA A 276
 None
 0.93A 3uniB-1rblA:
undetectable		 3uniB-1rblA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 GLY A 166
GLY A 196
ASN A 420
MET A 387
 None
 0.97A 3v3nB-1rblA:
2.1		 3v3nB-1rblA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 GLY A 166
GLY A 196
ASN A 420
MET A 387
 None
 0.97A 3v3nC-1rblA:
undetectable		 3v3nC-1rblA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus;
Synechococcus
elongatus) 		4 / 7 GLU A 433
TYR M  32
ARG A 431
GLY A 166
 None
 0.95A 4fgzA-1rblA:
undetectable		 4fgzA-1rblA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 7 ILE A 309
LEU A 314
PHE A 274
GLY A 273
 None
 1.02A 4hajA-1rblA:
undetectable		 4hajA-1rblA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 8 ILE A 309
LEU A 314
ILE A 116
PHE A 274
GLY A 273
 None
 1.19A 4hb6A-1rblA:
undetectable		 4hb6A-1rblA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 8 ILE A 309
LEU A 314
ILE A 116
PHE A 274
GLY A 273
 None
 1.22A 4hb8A-1rblA:
undetectable		 4hb8A-1rblA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus;
Synechococcus
elongatus) 		3 / 3 LEU M  18
PRO M  19
ARG A 435
 None
 0.65A 4klrB-1rblM:
undetectable		 4klrB-1rblM:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus) 		4 / 8 ASN A 420
GLU A 425
TYR M  17
TYR A 165
 None
 1.07A 4mj8A-1rblA:
undetectable
4mj8C-1rblA:
undetectable		 4mj8A-1rblA:
18.04
4mj8C-1rblA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 9 ALA A 389
GLY A 442
ILE A 444
ILE A 382
VAL A 332
 None
 1.16A 4nptA-1rblA:
undetectable		 4nptA-1rblA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		6 / 12 LEU A 170
LEU A 455
ALA A 458
ALA A 423
VAL A 384
GLY A 416
 None
 1.29A 4rn6B-1rblA:
undetectable		 4rn6B-1rblA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 TYR A 239
GLU A 158
GLY A 237
PRO A 152
LEU A 280
 None
 1.18A 4wcxC-1rblA:
2.9		 4wcxC-1rblA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 12 GLY A 373
GLU A 158
GLY A 154
SER A 321
LEU A 326
 None
 0.82A 4yvgA-1rblA:
undetectable		 4yvgA-1rblA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ARG A  41
HIS A 310
ARG A 134
 None
 1.06A 5iaoC-1rblA:
undetectable		 5iaoC-1rblA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		3 / 3 ARG A  41
HIS A 310
ARG A 134
 None
 1.11A 5iaoF-1rblA:
0.0		 5iaoF-1rblA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus) 		5 / 9 ILE M  30
VAL M 117
GLU M  86
ASP M  85
ILE M  42
 None
 1.44A 5lg3C-1rblM:
0.0		 5lg3C-1rblM:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)
(Synechococcus
elongatus) 		5 / 9 ILE M  30
VAL M 117
GLU M  86
ASP M  85
ILE M  42
 None
 1.50A 5lg3D-1rblM:
0.0		 5lg3D-1rblM:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 6 THR A  26
TYR A  85
TYR A 103
PHE A 364
 None
 1.04A 5lrbA-1rblA:
undetectable		 5lrbA-1rblA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 11 LEU A 326
GLY A 329
LEU A 318
ARG A 312
ALA A 315
 None
CAP  A 476 ( 4.3A)
None
None
None
 1.13A 5o96A-1rblA:
undetectable
5o96B-1rblA:
3.5		 5o96A-1rblA:
20.44
5o96B-1rblA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 6 THR A  75
ASP A  76
ARG A  79
ASP A 106
 None
 1.00A 5tdzA-1rblA:
2.2		 5tdzA-1rblA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 8 HIS A 386
GLN A 401
GLY A 171
LEU A 170
 None
 0.91A 5w3jB-1rblA:
undetectable		 5w3jB-1rblA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 6 PHE A  42
ARG A  41
ARG A 134
LEU A 133
 None
 1.06A 6b89B-1rblA:
undetectable		 6b89B-1rblA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		4 / 6 TRP A 385
ALA A 458
LEU A 455
ALA A 423
 None
 1.23A 6fosB-1rblA:
undetectable		 6fosB-1rblA:
8.94