SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		4 / 7 GLY A1106
LEU A1154
ALA A1151
TYR A1108
 None
 0.91A 1dmaA-1rc6A:
undetectable		 1dmaA-1rc6A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		4 / 6 PHE A1076
ILE A1039
PRO A1040
PHE A1119
 None
 1.27A 4fgkA-1rc6A:
undetectable		 4fgkA-1rc6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		4 / 8 GLY A1041
GLY A1071
LEU A1066
VAL A1064
 None
 0.91A 4fgzA-1rc6A:
undetectable		 4fgzA-1rc6A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		3 / 3 GLY A1114
GLU A1082
THR A1083
 None
 0.53A 4kouA-1rc6A:
0.0		 4kouA-1rc6A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		4 / 7 GLY A1080
GLY A1114
SER A1115
GLU A1079
 None
 0.66A 5ergB-1rc6A:
undetectable		 5ergB-1rc6A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		5 / 8 TYR A1251
LEU A1184
ILE A1206
PHE A1186
GLY A1238
 None
 1.45A 5eseA-1rc6A:
undetectable		 5eseA-1rc6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		5 / 8 TYR A1251
LEU A1184
PHE A1247
ILE A1206
GLY A1238
 None
 1.35A 5eseA-1rc6A:
undetectable		 5eseA-1rc6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1rc6 HYPOTHETICAL PROTEIN
YLBA
(Escherichia
coli) 		4 / 8 ARG A1134
THR A1052
PRO A1053
ILE A1049
 None
 1.11A 6a4iA-1rc6A:
undetectable		 6a4iA-1rc6A:
20.30