SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
3 / 3 THR A 184
GLU A  69
ASP A  47
None
0.84A 1nt2A-1rc9A:
undetectable
1nt2A-1rc9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
1.01A 1v54N-1rc9A:
undetectable
1v54W-1rc9A:
undetectable
1v54N-1rc9A:
17.70
1v54W-1rc9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
3 / 3 ASP A  47
THR A 184
GLU A  69
None
0.68A 2zifB-1rc9A:
undetectable
2zifB-1rc9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
0.97A 3ag4N-1rc9A:
undetectable
3ag4W-1rc9A:
undetectable
3ag4N-1rc9A:
17.70
3ag4W-1rc9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 4 THR A 159
VAL A  29
GLY A 164
THR A 165
None
1.08A 3cflA-1rc9A:
undetectable
3cflA-1rc9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
5 / 10 GLY A  74
ALA A 150
ILE A 119
PRO A 160
THR A 157
None
1.03A 3el9B-1rc9A:
undetectable
3el9B-1rc9A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 4 PRO A  31
TYR A 161
GLY A 164
THR A 165
None
1.45A 3ib0A-1rc9A:
undetectable
3ib0A-1rc9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
1.04A 3wg7A-1rc9A:
undetectable
3wg7J-1rc9A:
undetectable
3wg7A-1rc9A:
17.70
3wg7J-1rc9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 8 SER A  62
SER A  61
GLY A  74
GLN A 146
None
0.81A 4af0A-1rc9A:
undetectable
4af0A-1rc9A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
3 / 3 PRO A  31
TYR A 161
GLY A 164
None
0.71A 4g2zA-1rc9A:
undetectable
4g2zA-1rc9A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 8 ILE A  14
GLU A  13
GLU A  17
LEU A  21
None
0.81A 4mj8A-1rc9A:
undetectable
4mj8A-1rc9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 7 ASN A  48
GLN A 146
VAL A 144
GLU A  75
None
0.82A 4mv7A-1rc9A:
undetectable
4mv7A-1rc9A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 7 GLY A 114
TYR A 147
ASN A 152
HIS A 115
None
1.18A 4ws0A-1rc9A:
undetectable
4ws0A-1rc9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
1.06A 5b1aN-1rc9A:
undetectable
5b1aW-1rc9A:
undetectable
5b1aN-1rc9A:
17.70
5b1aW-1rc9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 8 THR A 157
PRO A 160
TYR A 161
VAL A  29
None
0.99A 5nzyA-1rc9A:
undetectable
5nzyA-1rc9A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
0.98A 5xdqA-1rc9A:
undetectable
5xdqJ-1rc9A:
undetectable
5xdqA-1rc9A:
17.70
5xdqJ-1rc9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri)
4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
None
1.02A 6nmfN-1rc9A:
undetectable
6nmfW-1rc9A:
undetectable
6nmfN-1rc9A:
17.70
6nmfW-1rc9A:
11.01