SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rcd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1rcd L FERRITIN
(Rana
catesbeiana) 		3 / 3 THR A 140
LEU A 144
LEU A 151
 None
 0.40A 1mz9C-1rcdA:
undetectable		 1mz9C-1rcdA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 1rcd L FERRITIN
(Rana
catesbeiana) 		5 / 12 PHE A 128
LEU A  65
TYR A  68
LEU A 110
LEU A 134
 None
 1.48A 1p33A-1rcdA:
undetectable		 1p33A-1rcdA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 1rcd L FERRITIN
(Rana
catesbeiana) 		5 / 12 PHE A 128
LEU A  65
TYR A  68
LEU A 110
PRO A 132
 None
 1.24A 1p33A-1rcdA:
undetectable		 1p33A-1rcdA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1rcd L FERRITIN
(Rana
catesbeiana) 		4 / 7 HIS A 124
TYR A  68
LEU A  16
GLN A  69
 None
 1.10A 1qzrA-1rcdA:
undetectable		 1qzrA-1rcdA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 1rcd L FERRITIN
(Rana
catesbeiana) 		4 / 7 HIS A 124
TYR A  68
LEU A  16
GLN A  69
 None
 1.10A 1qzrB-1rcdA:
undetectable		 1qzrB-1rcdA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1rcd L FERRITIN
(Rana
catesbeiana) 		5 / 8 PHE A 128
LEU A  65
TYR A  68
LEU A 110
LEU A 134
 None
 1.44A 2bfpC-1rcdA:
undetectable		 2bfpC-1rcdA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 1rcd L FERRITIN
(Rana
catesbeiana) 		4 / 8 SER A  26
ALA A  99
THR A 140
ILE A 141
 None
 0.90A 3bpxA-1rcdA:
1.6
3bpxB-1rcdA:
undetectable		 3bpxA-1rcdA:
19.34
3bpxB-1rcdA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1rcd L FERRITIN
(Rana
catesbeiana) 		3 / 3 LEU A  65
PHE A  24
ILE A  66
 None
 0.71A 5dzk1-1rcdA:
undetectable
5dzkF-1rcdA:
undetectable
5dzkM-1rcdA:
undetectable		 5dzk1-1rcdA:
1.79
5dzkF-1rcdA:
23.18
5dzkM-1rcdA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1rcd L FERRITIN
(Rana
catesbeiana) 		3 / 3 VAL A 116
GLN A  10
CYH A  12
 None
 0.70A 5icxA-1rcdA:
undetectable
5icxE-1rcdA:
undetectable		 5icxA-1rcdA:
21.36
5icxE-1rcdA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1rcd L FERRITIN
(Rana
catesbeiana) 		4 / 6 HIS A 114
TYR A  68
ARG A  72
HIS A 124
 None
 1.46A 5kkzA-1rcdA:
2.4
5kkzG-1rcdA:
undetectable		 5kkzA-1rcdA:
15.77
5kkzG-1rcdA:
26.15