SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rcw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 4 ASP A 196
LEU A 192
LEU A 131
LEU A 193
 None
 1.19A 1u18A-1rcwA:
undetectable		 1u18A-1rcwA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 12 LEU A  22
MET A  21
TYR A  27
ASP A 178
TYR A  43
 None
None
None
FE  A 402 (-2.7A)
None
 1.41A 2no6A-1rcwA:
0.0		 2no6A-1rcwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 12 GLY A  33
TYR A  27
ALA A 149
GLY A 155
LEU A 156
 None
 0.98A 3hs6B-1rcwA:
undetectable		 3hs6B-1rcwA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 PHE A 160
GLY A 161
PHE A 162
PHE A  95
 None
 1.11A 3ko0D-1rcwA:
1.2
3ko0E-1rcwA:
undetectable		 3ko0D-1rcwA:
18.30
3ko0E-1rcwA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_A_ACHA323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.44A 3rqwA-1rcwA:
undetectable
3rqwB-1rcwA:
undetectable		 3rqwA-1rcwA:
20.19
3rqwB-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_B_ACHB323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.43A 3rqwB-1rcwA:
undetectable
3rqwC-1rcwA:
undetectable		 3rqwB-1rcwA:
20.19
3rqwC-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_D_ACHD323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.42A 3rqwD-1rcwA:
undetectable
3rqwE-1rcwA:
undetectable		 3rqwD-1rcwA:
20.19
3rqwE-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_E_ACHE323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 ILE A 148
TYR A  43
LEU A  40
PHE A  26
PHE A  95
 None
 1.43A 3rqwA-1rcwA:
undetectable
3rqwE-1rcwA:
undetectable		 3rqwA-1rcwA:
20.19
3rqwE-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_F_ACHF323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.44A 3rqwF-1rcwA:
undetectable
3rqwG-1rcwA:
0.6		 3rqwF-1rcwA:
20.19
3rqwG-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_G_ACHG323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.42A 3rqwG-1rcwA:
0.6
3rqwH-1rcwA:
undetectable		 3rqwG-1rcwA:
20.19
3rqwH-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_H_ACHH323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 9 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.44A 3rqwH-1rcwA:
undetectable
3rqwI-1rcwA:
undetectable		 3rqwH-1rcwA:
20.19
3rqwI-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 8 PHE A  95
ILE A 148
TYR A  43
LEU A  40
PHE A  26
 None
 1.43A 3rqwI-1rcwA:
undetectable
3rqwJ-1rcwA:
undetectable		 3rqwI-1rcwA:
20.19
3rqwJ-1rcwA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		3 / 3 LEU A 201
GLU A 202
SER A 204
 None
 0.80A 4ccqA-1rcwA:
undetectable		 4ccqA-1rcwA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 8 ILE A 145
LEU A  78
VAL A 135
LEU A 138
 None
 0.83A 4r38B-1rcwA:
undetectable		 4r38B-1rcwA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1rcw CT610
(Chlamydia
trachomatis) 		5 / 12 SER A 143
LEU A 192
LEU A  74
ASN A  77
ALA A 137
 None
 1.18A 4x1kA-1rcwA:
undetectable
4x1kB-1rcwA:
undetectable		 4x1kA-1rcwA:
19.25
4x1kB-1rcwA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 LYS A 152
PHE A 214
TYR A  27
TYR A 141
 None
 1.35A 5a06A-1rcwA:
undetectable		 5a06A-1rcwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 LYS A 152
PHE A 214
TYR A  27
TYR A 141
 None
 1.37A 5a06C-1rcwA:
undetectable		 5a06C-1rcwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 LYS A 152
PHE A 214
TYR A  27
TYR A 141
 None
 1.36A 5a06D-1rcwA:
undetectable		 5a06D-1rcwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 LYS A 152
PHE A 214
TYR A  27
TYR A 141
 None
 1.34A 5a06E-1rcwA:
undetectable		 5a06E-1rcwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 7 LYS A 152
PHE A 214
TYR A  27
TYR A 141
 None
 1.37A 5a06F-1rcwA:
undetectable		 5a06F-1rcwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1rcw CT610
(Chlamydia
trachomatis) 		3 / 3 VAL A 207
SER A 204
TRP A 125
 None
 1.05A 5jwaA-1rcwA:
undetectable		 5jwaA-1rcwA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1rcw CT610
(Chlamydia
trachomatis) 		4 / 4 ASP A 178
HIS A 174
HIS A  88
HIS A 181
 FE  A 402 (-2.7A)
FE  A 401 (-3.4A)
FE  A 401 (-3.3A)
FE  A 402 (-3.5A)
 1.38A 5ncdD-1rcwA:
undetectable		 5ncdD-1rcwA:
21.22