SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		3 / 3 ASN 1 210
PHE 1 161
VAL 1 212
 GAL  1   1 (-2.9A)
None
GAL  1   1 ( 4.9A)
 0.83A 1kijA-1rdk1:
undetectable		 1kijA-1rdk1:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		3 / 3 ASP 1 158
VAL 1 221
PRO 1 143
 None
 0.71A 2avvA-1rdk1:
undetectable		 2avvA-1rdk1:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		4 / 8 PRO 1 213
SER 1 215
VAL 1 194
GLY 1 195
 CL  1   3 (-4.6A)
None
None
None
 0.80A 2qd3A-1rdk1:
undetectable		 2qd3A-1rdk1:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		4 / 8 PRO 1 213
SER 1 215
VAL 1 194
GLY 1 195
 CL  1   3 (-4.6A)
None
None
None
 0.81A 4mk4A-1rdk1:
undetectable		 4mk4A-1rdk1:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		4 / 6 ASP 1 166
THR 1 142
PRO 1 143
VAL 1 181
 CA  1 227 ( 2.4A)
None
None
None
 0.87A 4yoaA-1rdk1:
undetectable		 4yoaA-1rdk1:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		4 / 6 ASP 1 211
ASN 1 127
ASN 1 199
GLN 1 167
 CA  1   2 (-3.1A)
None
CA  1 227 (-3.4A)
None
 1.27A 5l6eA-1rdk1:
undetectable		 5l6eA-1rdk1:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rdk MANNOSE-BINDING
PROTEIN-C
(Rattus
rattus) 		4 / 5 ASN 1 171
ASP 1 166
ASN 1 199
ASN 1 192
 None
CA  1 227 ( 2.4A)
CA  1 227 (-3.4A)
GAL  1   1 (-2.7A)
 1.47A 5vooE-1rdk1:
undetectable		 5vooE-1rdk1:
18.66