SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A 420
ALA A 421
PHE A 432
LEU A 447
PRO A 448
 None
 1.04A 1og5A-1rdrA:
undetectable		 1og5A-1rdrA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A 420
ALA A 421
PHE A 432
LEU A 447
PRO A 448
 None
 1.06A 1og5B-1rdrA:
0.0		 1og5B-1rdrA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN A 301
ASN A 302
ILE A 324
GLY A 207
 None
 0.94A 1oniA-1rdrA:
undetectable
1oniB-1rdrA:
undetectable		 1oniA-1rdrA:
14.10
1oniB-1rdrA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN A 301
ASN A 302
ILE A 324
GLY A 207
 None
 0.95A 1oniD-1rdrA:
undetectable
1oniF-1rdrA:
undetectable		 1oniD-1rdrA:
14.10
1oniF-1rdrA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.10A 1p7lC-1rdrA:
undetectable		 1p7lC-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.10A 1p7lD-1rdrA:
undetectable		 1p7lD-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.12A 1rg9A-1rdrA:
undetectable		 1rg9A-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.11A 1rg9B-1rdrA:
undetectable		 1rg9B-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.10A 1rg9C-1rdrA:
undetectable		 1rg9C-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.10A 1rg9D-1rdrA:
undetectable		 1rg9D-1rdrA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.05A 1rxcC-1rdrA:
undetectable		 1rxcC-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.03A 1rxcD-1rdrA:
undetectable		 1rxcD-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 9 PHE A  34
VAL A 439
GLY A 442
VAL A 414
ILE A 401
 None
 1.18A 2a1oB-1rdrA:
undetectable		 2a1oB-1rdrA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.18A 2obvA-1rdrA:
undetectable		 2obvA-1rdrA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.16A 2p02A-1rdrA:
undetectable		 2p02A-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN A 301
SER A 298
ALA A 325
ASP A 329
 None
None
None
CA  A 501 (-3.4A)
 1.28A 3aruA-1rdrA:
undetectable		 3aruA-1rdrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 PHE A 230
SER A 333
THR A 312
LEU A 321
THR A 365
 None
 1.21A 3hj3C-1rdrA:
undetectable		 3hj3C-1rdrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 PRO A 214
PHE A 373
ALA A 209
 None
 0.66A 3itaD-1rdrA:
0.0		 3itaD-1rdrA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 ARG A 408
ASP A 412
ASP A 406
 None
 0.78A 3jayA-1rdrA:
undetectable		 3jayA-1rdrA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 ARG A 408
ASP A 412
ASP A 406
 None
 0.78A 3jb2A-1rdrA:
undetectable		 3jb2A-1rdrA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 ARG A 408
ASP A 412
ASP A 406
 None
 0.74A 3jb3A-1rdrA:
undetectable		 3jb3A-1rdrA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.06A 3kvvA-1rdrA:
undetectable		 3kvvA-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.03A 3kvvB-1rdrA:
undetectable		 3kvvB-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.00A 3kvvC-1rdrA:
undetectable		 3kvvC-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.00A 3kvvD-1rdrA:
undetectable		 3kvvD-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.03A 3kvvE-1rdrA:
undetectable		 3kvvE-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.07A 3kvvF-1rdrA:
undetectable		 3kvvF-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 LEU A 374
PHE A 373
ILE A 324
ALA A 325
 None
 0.70A 3mdrA-1rdrA:
undetectable		 3mdrA-1rdrA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A  85
ALA A 197
GLY A 192
ILE A 256
ILE A  90
 None
 0.80A 3s54A-1rdrA:
undetectable		 3s54A-1rdrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A  85
ALA A 197
GLY A 192
ILE A 256
ILE A  90
 None
 0.79A 3s54B-1rdrA:
undetectable		 3s54B-1rdrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		6 / 9 ASP A 238
ASN A 297
TYR A 326
GLY A 327
ASP A 328
ASP A 329
 None
None
None
None
None
CA  A 501 (-3.4A)
 0.68A 3sfuA-1rdrA:
22.8		 3sfuA-1rdrA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		6 / 9 ASP A 238
THR A 293
TYR A 326
GLY A 327
ASP A 328
ASP A 329
 None
None
None
None
None
CA  A 501 (-3.4A)
 0.74A 3sfuA-1rdrA:
22.8		 3sfuA-1rdrA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		7 / 9 ASP A 238
ASN A 297
TYR A 326
GLY A 327
ASP A 328
ASP A 329
LEU A 374
 None
None
None
None
None
CA  A 501 (-3.4A)
None
 0.66A 3sfuB-1rdrA:
23.3		 3sfuB-1rdrA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A 268
LEU A 253
ALA A 197
ALA A 196
TYR A 195
 None
 1.10A 3vw7A-1rdrA:
undetectable		 3vw7A-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 THR A 293
ASN A 297
GLY A 327
ILE A  17
 None
 0.98A 3w9tF-1rdrA:
undetectable		 3w9tF-1rdrA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.05A 4e1vB-1rdrA:
undetectable		 4e1vB-1rdrA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY A 207
GLN A  84
ARG A 306
ILE A 324
 None
 1.09A 4e1vF-1rdrA:
undetectable		 4e1vF-1rdrA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 HIS A 199
GLY A 292
ILE A 295
 None
 0.48A 4k50A-1rdrA:
36.7		 4k50A-1rdrA:
56.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		3 / 3 HIS A 199
GLY A 292
ILE A 295
 None
 0.48A 4k50I-1rdrA:
36.7		 4k50I-1rdrA:
56.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.18A 4kttC-1rdrA:
undetectable		 4kttC-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.24A 4ndnA-1rdrA:
undetectable		 4ndnA-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.18A 4ndnC-1rdrA:
undetectable		 4ndnC-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 ASN A  18
ALA A 209
SER A 294
GLY A 203
PHE A 217
 None
 1.08A 4obwA-1rdrA:
undetectable		 4obwA-1rdrA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.15A 4odjA-1rdrA:
undetectable		 4odjA-1rdrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 305
 None
 0.83A 4txnA-1rdrA:
undetectable		 4txnA-1rdrA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 305
 None
 0.85A 4txnB-1rdrA:
undetectable		 4txnB-1rdrA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 305
 None
 0.84A 4txnC-1rdrA:
undetectable		 4txnC-1rdrA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY A 207
GLN A  84
ARG A 306
ILE A 305
 None
 0.82A 4txnD-1rdrA:
undetectable		 4txnD-1rdrA:
21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WZM_A_ACTA503_0
(RNA DEPENDENT RNA
POLYMERASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 4 ASP A 233
ASP A 358
ASP A 329
ALA A 357
 CA  A 501 (-3.3A)
None
CA  A 501 (-3.4A)
None
 1.45A 4wzmA-1rdrA:
25.8		 4wzmA-1rdrA:
33.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 5a1iA-1rdrA:
undetectable		 5a1iA-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 5a1iA-1rdrA:
undetectable		 5a1iA-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU A  85
ALA A 197
GLY A 192
ILE A 256
ILE A  90
 None
 0.78A 5e5jB-1rdrA:
undetectable		 5e5jB-1rdrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
GLY A 425
VAL A 391
HIS A 389
 None
 0.77A 5f8yA-1rdrA:
0.0		 5f8yA-1rdrA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
GLY A 425
VAL A 391
HIS A 389
 None
 0.77A 5f8yB-1rdrA:
0.0		 5f8yB-1rdrA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.11A 5t8sB-1rdrA:
undetectable		 5t8sB-1rdrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 6 ILE A 316
TYR A 334
LEU A 321
ARG A 306
 None
 0.97A 6f6jA-1rdrA:
undetectable		 6f6jA-1rdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.17A 6fbnB-1rdrA:
undetectable		 6fbnB-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.14A 6fboA-1rdrA:
undetectable		 6fboA-1rdrA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.23A 6fcbA-1rdrA:
undetectable		 6fcbA-1rdrA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.12A 6fcdA-1rdrA:
undetectable		 6fcdA-1rdrA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1rdr POLIOVIRUS 3D
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS A 423
PRO A 390
PHE A 461
ASP A 215
 None
 1.13A 6g6rA-1rdrA:
undetectable		 6g6rA-1rdrA:
23.86