SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		4 / 7 PHE A  21
PHE A  27
SER A  18
ALA A  68
 None
 1.07A 1fxhA-1rduA:
undetectable
1fxhB-1rduA:
undetectable		 1fxhA-1rduA:
23.39
1fxhB-1rduA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		4 / 8 PHE A  21
PHE A  27
SER A  18
ALA A  68
 None
 1.01A 1pnlA-1rduA:
undetectable
1pnlB-1rduA:
undetectable		 1pnlA-1rduA:
23.39
1pnlB-1rduA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		3 / 3 ASP A  19
GLU A  90
GLY A  91
 None
 0.57A 3w9tA-1rduA:
undetectable		 3w9tA-1rduA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		4 / 6 GLY A  91
ARG A 105
GLU A 107
ARG A  88
 None
 1.19A 4bqfA-1rduA:
undetectable		 4bqfA-1rduA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		5 / 12 PHE A  21
ALA A  75
ILE A  44
PHE A  27
VAL A  59
 None
 0.87A 5uanB-1rduA:
undetectable		 5uanB-1rduA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1rdu CONSERVED
HYPOTHETICAL PROTEIN
(Thermotoga
maritima) 		5 / 10 LEU A  58
VAL A  63
ILE A  67
ALA A  68
ALA A  24
 None
 1.38A 6h1lA-1rduA:
undetectable		 6h1lA-1rduA:
12.76