SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1re0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 142
ALA B 117
GLY B 120
PHE B 141
 None
 0.87A 2wq5A-1re0B:
undetectable		 2wq5A-1re0B:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 4 PHE B 192
LYS B 191
ILE B 204
THR B 153
 None
 1.28A 3ia4B-1re0B:
undetectable		 3ia4B-1re0B:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		5 / 12 PHE B 174
LEU B 189
ILE B 185
ALA B 207
SER B 209
 None
 1.17A 4a83A-1re0B:
undetectable		 4a83A-1re0B:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		3 / 3 ASN B 145
LEU B 157
PHE B 143
 None
 0.81A 4dajB-1re0B:
undetectable		 4dajB-1re0B:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 179
ASP B 182
ARG B 186
ILE B 309
 None
 1.38A 4mwrA-1re0B:
undetectable		 4mwrA-1re0B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1re0 ARF
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 7 ASP B 215
GLN B 216
PRO B 246
ILE B 187
 None
 1.04A 4pcuA-1re0B:
undetectable		 4pcuA-1re0B:
16.76